Protein Secretion Pathway

Also called

protein secretion · secretory pathway · endomembrane system · rough endoplasmic reticulum · ribosome · ER lumen · transport vesicle · Golgi apparatus · cis face and trans face · secretory vesicle · exocytosis · lysosome · glycosylation · vesicle budding · अंतर्द्रव्यी जालिका · गॉल्जीकाय · लयनकाय

Topics

• The endomembrane system is the ER, Golgi complex, lysosomes and vacuoles working together as one pathway.
• Ribosomes on the rough ER make proteins that pass into the ER lumen as they are built.
• Proteins fold in the ER lumen and leave in small transport vesicles that bud off its membrane.
• Vesicles fuse with the cis (forming) face of the Golgi; modified proteins leave from the trans (maturing) face.
• The Golgi packages proteins and adds sugars to them (glycoproteins) before sending them on.
• Secretory vesicles fuse with the plasma membrane and release their contents outside: exocytosis.
• Lysosomes are vesicles packaged by the Golgi, rich in enzymes that digest worn-out organelles and food.
• The nucleus holds the DNA whose messages the ribosomes read; it sits beside the rough ER.

About this model

A GLB file of about 392 KB, shown in Lably's 3D viewer and, on a phone, placed in your room with AR. Credit: Model, science and animation: Lably (built procedurally with three.js; no downloaded meshes). | CC BY 4.0. Original geometry and animation made for Lably.

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