3,4-Dihydroxyphenylglycolaldehyde
Neurotransmitter metabolite and neurotoxin
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Through Metabolite and Redox
Formation
DOPEGAL is formed by monoamine oxidase (MAO) via oxidative deamination. Following its formation, DOPEGAL is metabolized. Through the metabolism process, it is converted into 3,4-dihydroxymandelic acid (DHMA) via aldehyde dehydrogenase (ALDH), or into 3,4-dihydroxyphenylglycol (DHPG) via aldehyde reductase (ALR).
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