Adapalene/benzoyl peroxide
Pharmaceutical combination
- 1 min read
- 2 chapters
Related on Lably
Through Skin and Combustion
Adapalene/benzoyl peroxide (Epiduo Gel) was approved for medical use in the United States in December 2008. Adapalene/benzoyl peroxide (Epiduo Forte) with a stronger adapalene strength was approved for medical use in the United States in July 2015. Adapalene/benzoyl peroxide (Differin Epiduo Acne Gel) is an over-the-counter version of Epiduo Gel that was approved for medical use in the United States in May 2026.
It is available as a generic medication. In 2023, it was the 319th most commonly prescribed medication in the United States, with more than 200,000 prescriptions.
Medical uses
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris.
Sign in to keep reading
One more chapter is free with a Lably account.
Side effects
Commonly reported side effects include the following:
- Skin redness
- Scaling
- Dry skin
- Contact dermatitis
- Skin irritation
- Stinging
- Burning

