Advanced airway management

Extraglottic airways

Extraglottic airway devices (EGDs) create a patent airway without entering the trachea. These devices are highly effective for providing oxygenation and ventilation. They can be used as primary airway devices, such as during CPR, or as rescue devices in situations where securing an airway using other devices has failed. EGDs are especially effective rescue devices for obese patients and patients with significant facial trauma. EGDs do not protect the trachea from obstruction or aspiration. They may be used for several hours until a definitive airway can be secured.

Each type of EGD has different features, including the ability to remove air from the stomach (gastric decompression) and perform tracheal intubation. All EGDs can be placed without directly seeing the glottis (also called "blind" placement). EGDs can be classified into supraglottic airways and retroglottic airways.

Supraglottic airways

Supraglottic airway devices (SGAs) create a seal over the glottic opening to route oxygen directly into the trachea. The SGAs consist entirely of laryngeal masks. Several manufacturers produce these devices, the most well known being the laryngeal mask airway (LMA). Success rates of SGAs in securing airways are similar between the different models, and these devices provide effective ventilation in more than 98% of patients. SGAs can be placed in under 30 seconds, making them advantageous for emergency use. Serious complications are rare and usually result from nerve and soft tissue trauma in the pharynx during placement.

Retroglottic airways

Retroglottic airway devices (RGAs) pass behind the glottis and into the esophagus to create a seal allowing oxygen to be delivered directly to the trachea. The RGAs are designed as laryngeal tubes. Examples of RGAs include the Combitube and the King LT. Studies comparing the effectiveness between the RGAs are lacking. Like SGAs, most complications from RGAs result from trauma to the pharynx during placement.

Tracheal intubation

Tracheal intubation, often simply referred to as intubation, is the placement of a flexible plastic or rubber endotracheal tube (ETT) into the trachea to maintain an open airway, allow for effective ventilation, protect the airway from aspiration (when a cuffed ETT is used), and to serve as a conduit through which to administer inhaled anesthetics. It is frequently performed in surgery, critically injured, ill or anesthetized patients to facilitate ventilation of the lungs, including mechanical ventilation, and to prevent the possibility of asphyxiation or airway obstruction. The most widely used route is orotracheal intubation, in which an endotracheal tube is passed through the mouth, through the vocal cords, and into the trachea. In a nasotracheal intubation, a nasotracheal tube (NTT) is passed through the nose, through the vocal cords, and into the trachea.

Indications

There are specific indications or guidelines for deciding a more invasive and more secure airway is worth the associated risk:

• respiratory failure
• apnea or the suspension of breathing
• decreased or altered level of consciousness, rapid mental status change, Glasgow Coma Scale score less than 8 (GCS<8).
• major trauma, such as penetrating injury to the abdomen or chest
• direct airway injury or facial burns
• high risk of aspiration

Methods

Direct Laryngoscopy

Classically, tracheal intubation has been performed utilizing direct laryngoscopy to obtain direct visualization of the vocal cords. There are multiple different laryngoscope blade styles, shapes, and lengths from which to choose based on patient anatomy and clinician preference. In North America, the Macintosh blade is the most commonly used curved blade while the Miller blade is the most common straight blade. Many modern laryngoscopes are equipped with a fiberoptic light source to aid in visualization. Regardless of blade shape, direct laryngoscopy technique involves passage of the laryngoscope through the mouth and into the back of the throat. Manipulation of the neck and lifting of the tongue allows for direct visualization of the larynx and vocal cords by the operator. Following visualization, the endotracheal tube can be passed along the blade, through the vocal cords, and into the trachea. Adjuncts such as a bougie (tracheal introducer) or stylet may be used to assist with endotracheal tube placement, particularly in cases where visualization of the vocal cords is limited. A bougie can be advanced into the trachea first, with the endotracheal tube subsequently railroaded over it.

Rapid Sequence Induction (RSI)

Rapid sequence induction (RSI) is a technique used to facilitate tracheal intubation in patients at high risk of aspiration or with respiratory failure. RSI involves the administration of a rapid-acting sedative (induction agent) followed immediately by a neuromuscular blocking agent to induce unconsciousness and paralysis, allowing prompt placement of an endotracheal tube while minimizing the risk of gastric aspiration. Bag-mask ventilation is often limited prior to intubation to reduce gastric insufflation. RSI is commonly performed in emergency medicine, critical care, and trauma settings.

Video Laryngoscopy

Multiple intubation tools are now available with built-in video technology, also known as video laryngoscopy. The GlideScope model utilizes a curved laryngoscopic blade with an integrated camera connected to a large external monitor. The McGrath model has a compact design with a small display directly attached to the laryngoscopic blade. The operator introduces the video laryngoscope through the mouth with a technique similar to direct laryngoscopy. The larynx and vocal cords are visualized via the camera and the operator is able to pass the endotracheal tube through the vocal cords and into the trachea under direct visualization on the video monitor. Studies have shown that when compared to direct laryngoscopy, video laryngoscopy resulted in fewer failed intubation attempts, especially in patients with known difficult airways. Limitations of video laryngoscopy exist and prevent the exclusive use of this method over direct laryngoscopy. Excessive blood and saliva in the airway can cover the camera lens on the video laryngoscope and obscure effective visualization of the anatomy, preventing effective intubation attempts. This is of importance in patients with trauma to their airway, increasing the amount of blood present, and patients taking sialogogues, or drugs that increase the flow of saliva.

Fiberoptic Intubation

In patients with known difficult airways, fiberoptic intubation can be considered. This technique involves the use of a flexible fiberoptic bronchoscope for visualization of the vocal cords. The bronchoscope can be passed directly into the trachea and the endotracheal tube can be threaded over the bronchoscope into position. This technique has various advantages over direct laryngoscopy and video laryngoscopy techniques. The fiberoptic scope is flexible and can be directed by the operator, allowing it to traverse the upper airway with minimal manipulation of the patient's neck. The operator can manipulate the device around obstructions in the upper airway, making the technique advantageous for patients with cancer or swelling in the upper airway. The device is relatively small compared to a laryngoscope and can therefore be implemented in patients with small mouth openings. Additionally, the fiberoptic scope can be passed through the nostril to provide visualization for a nasotracheal intubation. Lastly, fiberoptic intubation can be conducted in an awake patient with sufficient use of local anesthetics, which can prove useful in patients who would otherwise be unable to be anesthetized without having a secure airway in place beforehand.

Less Common Methods

There are a variety of less commonly used methods of intubation and ventilating a patient, which even includes methods avoiding tracheal intubation. Some of the more popular techniques include Lightwand intubation that uses an LED lit stylet to transilluminate the soft tissues of the neck if correctly placed in the trachea and then inserting an endotracheal tube through it. The Lightwand was originally developed for use in the military where a blood in the airway may obstruct an effective view of the glottis.

Utilization of transtracheal jet ventilation is often used independently in cases where an endotracheal tube may be obstruct the surgeon from working in the oral cavity or airway (i.e. maxillofacial surgery or ear, nose, and throat [ENT] surgery). The process entails low tidal volume and high-frequency ventilation via a laryngeal catheter to ventilate a patient. It can be utilized when a difficult airway is anticipated but it is not recommended to be used as a part of the difficult airway algorithm when a patient cannot be otherwise intubated or ventilated.

Confirming placement

It is necessary to confirm placement of the endotracheal tube to ensure that the tube is properly positioned within the trachea and has not accidentally passed into the esophagus instead. Additionally, it is important to confirm that the endotracheal tube was not placed too deep in the trachea where is may only be ventilating one of the lungs due to it being positioned within a mainstem bronchi (frequently the right mainstem bronchi due to a more obtuse angle than the left). The gold standard for confirming successful placement of an endotracheal tube is direct visualization of the tube passing through the vocal cords and continuous positive waveform end-tidal carbon dioxide on capnography. Secondary methods of confirmation include oxygen saturation, chest x-ray, ultrasound, condensation in the endotracheal tube, equal chest rise, breath sounds heard on both sides of the chest (often with the assistance of a large tidal volume breath), and an absence of breath sounds over the epigastrium. No single method of confirming placement is 100% reliable so multiple methods of confirmation should be utilized.

Surgical airways

Surgical methods for airway management rely on making a surgical incision below the glottis in order to achieve direct access to the lower respiratory tract, bypassing the upper respiratory tract. Surgical airway management is performed as a last resort in cases where tracheal intubation has failed, is not feasible, or is contraindicated. Surgical methods for airway management include cricothyrotomy and tracheotomy.

Cricothyrotomy

A cricothyrotomy is a procedure during which an incision is made through the cricothyroid membrane, allowing an artificial airway to be placed in the trachea. It is the first-line surgical procedure to access an airway in an emergency because it can be performed more quickly than a tracheotomy and is less likely to cause bleeding and damage to thyroid tissue. A cricothyrotomy creates a temporary airway that can be used until a more definitive airway can be secured. A cricothyrotomy is typically performed as an emergency procedure when other airway management attempts have failed and the patient is at risk of asphyxiation. The most common acute complications are bleeding, tracheal cartilage laceration, tracheal perforation, infection, subglottic stenosis, and voice changes. The procedure is frequently performed by an otorhinolaryngologist (an ear, nose, and throat surgeon) if available or an anesthesiologist.

Tracheotomy

A tracheotomy is a surgical procedure creating an incision in the front of the neck down to the trachea. A tracheostomy tube can be placed through the opening created by the incision, which allows breathing through the tube rather than the nose and mouth. Although the terms are sometimes used interchangeably, a "tracheotomy" is the surgical procedure creating an incision into the trachea, while "tracheostomy" refers to the opening in the trachea created by the incision. The most common acute complications of a tracheotomy are difficulty speaking or swallowing due to nerve damage, prolonged bleeding at the incision site, and pneumothorax. A tracheotomy is rarely indicated in an emergent setting. It more commonly performed in a controlled environment to create an airway that can be used long-term, such as for prolonged mechanical ventilation.

Difficult airway algorithm

Various expert societies in airway management, including the American Society of Anesthesiologists, have recommended approaches to difficult airways. The algorithm provides a step-by-step framework to respond to situations where traditional airway management techniques may be inadequate. Current guidelines for airway management when inducing anesthesia where ventilation is inadequate recommend to call for help and limit attempts at tracheal intubation to three attempts plus one attempt by an experienced provider (3 + 1 rule) in order to prevent unnecessary trauma. The “3 + 1 rule” refers to a maximum of three attempts by the initial operator, followed by one additional attempt by a more experienced clinician before proceeding to alternative airway strategies. If direct laryngoscopy was utilized initially it is recommended to consider video laryngoscopy. This is followed by attempting bag mask ventilation then by placing a supraglotic airway, usually a laryngeal mask airway. If ventilation is still inadequate, it is recommended to consider an emergency invasive airway such as a surgical airway, rigid bronchoscopy, or extracorporeal membrane oxygenation (ECMO). Invasive airways should be performed by an individual well-trained in invasive airway techniques whenever possible. While preparing for invasive airway placement, it is recommended to continue to attempt alternative methods of tracheal intubation beyond the normally recommended 3 + 1 rule.

Training and Competency

Advanced airway management requires formal training and ongoing competency assessment. Clinicians performing advanced airway procedures are typically trained in anesthesiology, emergency medicine, critical care, or prehospital emergency care. Simulation-based training, supervised clinical experience, and maintenance of procedural volume are important to ensure proficiency and reduce complications. Skill decline may occur if advanced airway techniques are performed infrequently, emphasizing the importance of continued education and practice.

Pediatric considerations

Many advanced airway techniques may be applied to children. In the fields of pediatric anesthesiology, pediatric critical care, and pediatric emergency medicine, a clear passage between the lungs and the environment is essential.

Children have numerous anatomic differences from adults which present unique challenges when implementing advanced airway techniques. Neonates and infants have overall smaller airway anatomy including a shorter trachea and smaller nasal openings. Additionally, they have proportionally larger tongues and heads. As a result, infants are obligate nasal breathers until the age of 5 months. Given their overall smaller airway diameter, children are more susceptible to airway obstruction from swelling. Given the rapid growth throughout childhood, care must be taken to choose the proper sized airway device for every individual. Broselow tape is a tool used to help facilitate rapid and accurate equipment sizing decisions in pediatric emergency situations.

Supraglottic airway devices, direct laryngoscopy, indirect video laryngoscopy, and fiberoptic intubation are all techniques which can be used to secure the pediatric airway. In the event that these techniques cannot adequately ventilate the patient, a surgical airway may be required. Surgical help should be requested for invasive access, however, in scenarios in which a pediatric otorhinolaryngologist is not available, a needle cricothyrotomy is an emergency alternative.