Aminoacetonitrile
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Through Organic compound and Ammonium
Production and applications
Industrially aminoacetonitrile is produced from glycolonitrile by reaction with ammonia:
- HOCH2CN + NH3 → H2NCH2CN + H2O
The aminoacetonitrile can be hydrolysed to give glycine: Being bifunctional, it is useful in the synthesis of diverse nitrogen-containing heterocycles.
Aminoacetonitrile derivatives are useful antihelmintics. They act as nematode specific ACh agonists causing a spastic paralysis and rapid expulsion from the host.
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Occurrence in the interstellar medium
Using radio astronomy, aminoacetonitrile was discovered in the Large Molecule Heimat, a giant gas cloud near the Galactic Center in the constellation Sagittarius. This discovery is significant to the debate on whether glycine exists widely in the universe.