Artesunate/amodiaquine

Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough. Safety in pregnancy is not clear; however, the medication may be used if others are not possible. It is believed to be safe for use during breastfeeding. Artesunate and amodiaquine are both antimalarial medication; however, work by different mechanisms.

Artesunate/amodiaquine was commercially launched in 2007. It is on the World Health Organization's List of Essential Medicines. Artesunate/amodiaquine is available as a generic medication. As of 2014 it is not commercially available in the United States or United Kingdom.

Medical uses

Early clinical trials showed that a once-a-day dosage was effective. It was subsequently clinically shown to be equally effective as artemether/lumefantrine, although it is likely to be more effective in the field due to its simpler once-a-day dosage compared to artemether/lumefantrine twice-per-day dosage.