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Barbara E. Jones

Canadian neuroscientist

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Through Sleep

Education and career

Jones was a student at the University of Delaware, earning a bachelor's degree in psychology in 1966, a master's degree in physiological psychology in 1969, and a Ph.D. in physiological psychology in 1971.

She joined the McGill University faculty as a professor in the Department of Neurology and Neurosurgery at the Montreal Neurological Institute and Hospital in 1977. During her career, Jones studied how the brain generates waking and sleep states using immunohistochemical and neuroanatomical techniques combined with neurophysiological recording, and optogenetics. Amongst many important findings, Jones identified the modulatory action of cholinergic neurons on cortical activation, the influence of inhibitory GABA neurons on sleep states and the activity of hypocretins/orexins neurons as key regulators of waking and narcolepsy with cataplexy in humans and animals.

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