Barbara Pearse
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Through England
Education
Barbara Pearse attended the independent Lady Eleanor Holles School in Hampton in Greater London, and gained her undergraduate degree from University College London in 1969.
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Career
She was appointed to the scientific staff of the MRC Laboratory of Molecular Biology in 1982.
Research
Pearse's main contributions lie in the structure of coated vesicles. Pearse first purified coated vesicles; she also discovered the clathrin coat molecule in 1975. Coated pits and vesicles were first seen in thin sections of tissue in the electron microscope by Thomas Roth and Keith Porter in 1964. The importance of them for the clearance of LDL from blood was discovered by R. G. Anderson, Michael S. Brown and Joseph L. Goldstein in 1976.
Personal life
She is married to Mark Bretscher, another scientist.