Lably
Skip to content

Bifemelane

Antidepressant and cerebral activator drug

  • 1 min read
  • 1 chapters

Related on Lably

Through Dementia and Brain

Lab · Class 10–11Inside the BrainLab · Class 10–11Neural ControlLab · Class 11Neural Control and Coordination — Animated Chapter FilmLab · Class 11One Day Inside the Human Body — Animated Chapter Film

Bifemelane acts as a monoamine oxidase inhibitor (MAOI) of both isoenzymes, with competitive reversible inhibition of MAO-A (Ki = 4.20 μM), making it a reversible inhibitor of monoamine oxidase A (RIMA) and non-competitive irreversible inhibition of MAO-B (Ki = 46.0 μM), and also acts (weakly) as a norepinephrine reuptake inhibitor (NRI). The drug has nootropic, neuroprotective, and antidepressant-like effects in animal models, and appears to enhance the cholinergic system in the brain.

More in Health

Food and Drug AdministrationFederal agency of the United States Department of Health and Human ServicesCenters for Disease Control and PreventionUnited States government public health agencyNauseaMedical symptom or conditionSeizurePeriod of symptoms due to excessive or synchronous neuronal brain activityVomitingExpulsion of stomach contents via the mouth or noseIntravenous therapyMedication administered into a vein