Bladder sphincter dyssynergia

In a nutshell

Bladder sphincter dyssynergia (also known as detrusor sphincter dyssynergia (DSD) (the ICS standard terminology agreed 1998) and neurogenic detrusor overactivity (NDO)) is a consequence of a neurological pathology such as spinal injury or multiple sclerosis which disrupts central nervous system regulation of the micturition (urination) reflex resulting in dyscoordination of the detrusor muscles of the bladder and the male or female external urethral sphincter muscles. In normal lower urinary tract function, these two separate muscle structures act in synergistic coordination. But in this neurogenic disorder, the urethral sphincter muscle, instead of relaxing completely during voiding, dyssynergically contracts causing the flow to be interrupted and the bladder pressure to rise.

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Treatment

Botulinum A toxin is a valuable alternative for patients who do not want surgical methods.

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Food and Drug AdministrationFederal agency of the United States Department of Health and Human Services Centers for Disease Control and PreventionUnited States government public health agency NauseaMedical symptom or condition SeizurePeriod of symptoms due to excessive or synchronous neuronal brain activity VomitingExpulsion of stomach contents via the mouth or nose Intravenous therapyMedication administered into a vein