CYP2A6
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ToursExplore Lably’s 3D toursThe CYP2A6 gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
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Distribution
CYP2A6 localizes to the endoplasmic reticulum and is found predominantly in the liver.
Variability
Significant interindividual variability in CYP2A6 apoprotein and mRNA levels has been observed.
Induction
CYP2A6 is known to be inducible by phenobarbital and rifampicin, and it is suspected that other antiepileptic drugs may also have this effect.
CYP2A6 Ligands
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