Dieter Seebach
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Through Carbonyl group
Work
Seebach worked on dendrimer chemistry and on the synthesis of beta-peptides. The development of the umpolung, a polarity inversion of the carbonyl group, with 1,3-propanedithiol together with Corey had a big influence on organic synthesis, and subsequently the Corey-Seebach reaction was named after them.
The Fráter–Seebach alkylation, a diastereoselective reaction of beta-hydroxy esters, is named after him.
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Awards
- 2000 Marcel Benoist Prize
- 2003 Tetrahedron Prize for Creativity in Organic Chemistry & BioMedicinal Chemistry
- 2004 The Ryoji Noyori Prize
- 2019 Arthur C. Cope Award
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