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Dieter Seebach

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Through Carbonyl group

Work

Seebach worked on dendrimer chemistry and on the synthesis of beta-peptides. The development of the umpolung, a polarity inversion of the carbonyl group, with 1,3-propanedithiol together with Corey had a big influence on organic synthesis, and subsequently the Corey-Seebach reaction was named after them.

The Fráter–Seebach alkylation, a diastereoselective reaction of beta-hydroxy esters, is named after him.

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