Diflubenzuron
Chemical compound
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Through Moth and Carcinogen
Mechanism of action
The mechanism of action of diflubenzuron involves inhibiting the production of chitin which is used by an insect to build its exoskeleton. It triggers insect larvae to molt early without a properly formed exoskeleton, resulting in the death of the larvae.
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Mammalian toxicity
Diflubenzuron has been evaluated by the United States Environmental Protection Agency (EPA), and it is classified as non-carcinogenic. 4-Chloroaniline, a metabolite of diflubenzuron which has been classified as a carcinogen, is produced after diflubenzuron has been ingested. The small amount converted to 4-chloroaniline after ingestion is not sufficient to cause cancer.
Commercial uses
Diflubenzuron is used in many products for various purposes.
Dimilin was the first product sold with diflubenzuron as active ingredient. It is still sold as wettable powder (WP-25 ) and various concentrations as suspension concentrate (SC). It is used on a wide variety of crops and target insects.
Micromite (UPL corporation) is sold in two formulations: water dispersible granules (WGS) containing 80% diflubenzuron, and an emulsifiable concentrate (EC) containing 22% diflubenzuron. It is used on a wide variety of crops and target insects.
Adept (OHP, Inc.) is sold as a 25% wettable powder (WP) formulation for ornamental crops in greenhouses. It is used for the control of fungus gnats, shore flies, armyworms, leafminers and suppression of whiteflies.
Device (Arysta LifeScience) for vector control.
Clarifly (Central Garden & Pet) and JustiFly (Champion). are feed-through cattle treatments to control horn flies and face flies. Vigilante, formulated as a bolus for this purposeis no longer sold.