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DLX2

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Through Protein and Gene

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.

Interactions

DLX2 has been shown to interact with DLX5, MSX1 and Msh homeobox 2.

More in Biology

Source and licence. Adapted from the Wikipedia article “DLX2” (this version, 2023-01-29) by its contributors, shared under CC BY-SA 4.0. Lablypedia has left out its tables, references and most pictures, and linked it to other Lablypedia articles.