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Ecdysone

Precursor of an insect hormone

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Through Steroid, Hormone and Toxin

Ecdysone turns into 20-hydroxyecdysone by the activity of ecdysone 20-monooxygenase, which requires molecular oxygen and a reduced hydrogen acceptor (NADPH).

Ecdysone and other ecdysteroids also appear in many plants mostly as a protection agent (toxins or antifeedants) against herbivorous insects. Some phytoecdysteroids may be bioactive in human contexts such as n ecdysteroid precursor from Stachyurus himalaicus, which exhibits cytotoxicity Ecdysones from insects have also exhibited antioxidant properties on lipid peroxidation. Ecdysteroids are also found in the purport adaptogen Cordyceps militaris .

Tebufenozide, sold under the Bayer trademark MIMIC, has ecdysteroid activity although it bears little resemblance to the ecdysteroids.

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