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G12/G13 alpha subunits

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Related on Lably

Through Cytoskeleton and Cancer

G proteins G12 and G13 regulate actin cytoskeletal remodeling in cells during movement and migration, including cancer cell metastasis. G13 is also essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells.

Genes

  • GNA12 (GNA12)
  • GNA13 GNA13

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