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Genital tubercle

Body of tissue present in the development of the reproductive system

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Through Embryo, Fetus and Urethra

In the development of the male fetus, the two sides of the tubercle approach ventrally forming a hollow tube that encloses the male urethra. The two glans wings merge in the midline forming the septum glandis. In the female fetus, the tubercle is attached to the vestibular folds that remain unfused forming the labia minora and the vaginal vestibule in between. The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.

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