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GLIC

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Through Bacteria

Lab · Class 8Microorganisms ExplorerLab · Class 6–8The Science of CookingLabFibre to Fabric

The similarity of amino-acid sequence to the eukaryotic LGICs is not localized to any single or particular tertiary domain, indicating the similar function of the GLIC to its eukaryotic equivalents. Regardless, the purpose of regulating the threshold for action potential excitation in the nerve signal transmission of multicellular organisms cannot translate to single-cell organisms, thereby not making the purpose of bacterial LGICs immediately obvious.

Structure

The structure of the open channel structure was solved by two independent research teams in 2009 at low pH values of 4-4.6 (GLIC being proton-gated).

More in Human body

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Source and licence. Adapted from the Wikipedia article “GLIC” (this version, 2023-11-29) by its contributors, shared under CC BY-SA 4.0. Lablypedia has left out its tables, references and most pictures, and linked it to other Lablypedia articles.