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HCN4

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Through Protein, Gene and Heart

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There are four HCN channels. HCN4 is prominently expressed in the pace maker region of the mammalian heart. Some humans with bradycardia and Sick sinus syndrome have been shown to have mutations in their HCN4 gene. The role of HCN channels in autonomic control of heart rate is currently a matter of ongoing investigation.

Interactions

HCN4 has been shown to interact with HCN2.

More in Human body

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Source and licence. Adapted from the Wikipedia article “HCN4” (this version, 2023-08-18) by its contributors, shared under CC BY-SA 4.0. Lablypedia has left out its tables, references and most pictures, and linked it to other Lablypedia articles.