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History of St. Louis before 1762

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Through Christian mission

Early settlements

The earliest settlements in the St. Louis area were built by the people of the Mississippian culture, who constructed more than two dozen burial mounds within what would become the city of St. Louis. The earliest mounds in the area date to approximately 1050, but much about the mound builders in St. Louis is unknown. Although some of the St. Louis area settlement is preserved at the Cahokia Mounds site in Illinois, the mounds in St. Louis were nearly all demolished. Only one mound remains within the city (Sugarloaf Mound), although St. Louis retained the nickname "The Mound City" well into the 19th century.

One of the primary causes of settlement for indigenous peoples was the presence of the Mississippi River and its tributaries, especially the Missouri River. Native Americans used the large forests located along the river to construct canoes, which were then used for transport on the rivers. After the end of the Mississippian culture in the 14th century and due to pressures from French Canadian settlers, Siouan-speaking groups such as the Missouria and Osage migrated to the Missouri valley, living in villages along the Osage and Missouri rivers. Both groups lived in conflict with northeastern tribes such as the Sauk and Meskwaki, and all four groups confronted the earliest explorers of Missouri.

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