Left colic artery
Artery
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Structure
The left colic artery usually represents the dominant arterial supply to the left colic flexure.
Course
The left colic artery passes to the left posterior to the peritoneum. After a short but variable course, it divides into an ascending branch and a descending branch.
Branches and anastomoses
Ascending branch
The ascending branch passes superior-ward. It passes anterior to the (ipsilateral) psoas major muscle, gonadal vessels, ureter, and kidney; it passes posterior to the inferior mesenteric vein. Its terminal branches form anastomoses with those of the middle colic artery; it also forms anastomoses with the descending branch (of the left colic artery).
Descending branch
The descending branch passes inferolaterally. It forms anastomoses with the superior-most sigmoid artery as well as the ascending branch (of the left colic artery), thereby participating in the formation of the marginal artery of the colon.
Variation
The left colic artery may have a common origin with a sigmoid artery, or may arise by branching of from a sigmoid artery. Occasionally, the left colic artery may arise from either the superior mesenteric artery, the middle colic artery, or the proximal-most jejunal artery; rarely, an accessory left colic artery may arise from the aforementioned arteries. An accessory left colic artery may also arise from the left colic artery itself.
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Clinical significance
The left colic artery may be ligated during abdominal surgery to remove colorectal cancer. This may have poorer outcomes than preserving the artery.

