MAD2L1
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Function
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.
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Interactions
MAD2L1 has been shown to interact with:
- ADAM17,
- BUB1B,
- CDC20,
- CDC27 and
- Estrogen receptor beta,
- MAD2L2,
- Mad1, and
- UBD.
More in Biology
GenusTaxonomic rank above species and below familyFamily (taxonomy)Taxonomic rank between genus and orderEndemismState of species being unique to a locationCladeGroup of a common ancestor and all of their descendantsGenomeAll genetic material of an organismOrder (taxonomy)Taxonomic rank between class and family

