Matthew Sacchet
American neuroscientist
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Through Machine learning, Mental disorder and Psychology
Education
Sacchet received a Sc.B. in Contemplative Science from Brown University and a Ph.D. in Neurosciences from Stanford University.
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Academia
Career
Sacchet has held research positions at Brown University, Harvard University, McLean Hospital, Massachusetts General Hospital, Massachusetts Institute of Technology, University of Tübingen, and Stanford University. Since 2019, he has been faculty at Harvard Medical School and since 2022 Massachusetts General Hospital where he directs the Meditation Research Program. The Meditation Research Program is affiliated with the Department of Psychiatry and the Athinoula A. Martinos Center for Biomedical Imaging. The Meditation Research Program uses research approaches from affective and cognitive neuroscience, applied phenomenology, clinical psychology and psychiatry, computer science and related computational disciplines, contemplative and religious studies, engineering, epidemiology, neuroimaging and electrophysiology, philosophy, psychometrics and psychological assessment, and psychosomatic medicine. The Program's studies have included multidisciplinary investigation of meditative development and meditative endpoints toward a more comprehensive understanding of the trajectories and outcomes of advanced meditation. The Program has also published landmark research in domains including diverse theoretical aspects of advanced meditation research, and empirically including contributing first studies of advanced absorption ("jhana") and insight meditation, meditative endpoints (including cessations of consciousness), and the epidemiology and public health implications of altered states of consciousness. The goal of the Meditation Research Program is to establish a scientific understanding of, and also to share, advanced meditation as well as to "contribute to improving individual well-being and the collective health of society by informing the development of meditation training and meditation-based interventions that are more effective, efficient, and targeted."
Work
Sacchet's work has influenced several areas, including the science of meditation, brain connectivity in depression, machine learning and person-specific biomarkers for depression, and depression and the brain across the lifespan.

