Melanin-concentrating hormone receptor
InterPro Family
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Related on Lably
- MCH-R1 is expressed in all mammals.
- MCH-R2 is only found in some primates and carnivores including dogs, ferrets and humans.
Clinical significance
Antagonists might be useful in the treatment of obesity and anxiety and depression. An agonist might have possible utility as a treatment for osteoporosis and insomnia
Research is ongoing for antagonists affecting MCH receptors R1 and R2.
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