Mirati Therapeutics
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Mirati Therapeutics works largely in KRAS-mutation inhibition, and developing treatments for tumors that contain it. The inhibition to the mutation has shown to shrink the size of its tumors. The company is based in San Diego, California. The company’s name comes from the Italian word for “targeted” (Mirati). Mirati Therapeutics is traded on the Nasdaq under the ticker symbol MRTX. It joined the exchange in 2013.
In October 2023, Bristol Myers Squibb agreed to acquire the company in an all-cash deal worth $4.8 billion, and an additional $1 billion in milestone payment. The acquisition was completed in January 2024.
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Drug candidates
The company’s leading drug candidates are sitravatinib and adagrasib. Mirati also has a preclinical candidate against the G12D mutation.
Management
The company’s CEO and President is David Meek.

