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Mucin 5AC

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Through Protein, Gene and Respiratory tract

Lab · Class 11–12Biomolecules of LifeLab · Class 11Biomolecules — Animated Chapter FilmLab · Class 11Locomotion and Movement — Animated Chapter FilmLab · Class 4–6Food and Nutrition

MUC-5AC is a large gel-forming glycoprotein. In the respiratory tract, it protects against infection by binding to inhaled pathogens, which are subsequently removed by mucociliary clearance. Overproduction of MUC-5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease, and has also been associated with greater protection against influenza infection.

Clinical relevance

This gene has been linked to mucus hypersecretion in the respiratory tract and is associated to chronic obstructive pulmonary disease (COPD).

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