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Obesity and the environment

Environmental factors affecting the incidence of obesity

  • 22 min read
  • 9 chapters

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Environmental obesogens

Studies have shown that obesity has become increasingly prevalent in both people and animals (pets and laboratory animals). Proper diet and exercise is not linked to lower obesity rates or the trending toward obesity despite these being the assumed cure and preventative for obesity. According to Professor Robert H. Lustig from the University of California, San Francisco, "[E]ven those at the lower end of the body mass index (BMI) curve are gaining weight. Whatever is happening is happening to everyone, suggesting an environmental trigger." The theory of environmental obesogens proposes a different causal facet to obesity – that lifetime exposure to xenobiotic chemical obesogens, molecules that do not properly regulate lipid metabolism in the body and may cause obesity, changes the body's metabolic system. Data is scarce, but some in-vitro studies have found this model could be an accurate predictor of future obesity. A study suggested that smoking before and during pregnancy, for example, increases the risk of obesity twofold in children of school age.

Many chemicals in common-use products are known or suspected to be obesogens and act as endocrine disruptors in the body. In a University at Albany, State University of New York study, organotin compounds, toxic chemicals derived from tin and hydrocarbon substituents, were found in a designer handbag, vinyl blinds, wallpaper, tile, and vacuum cleaner dust collected from 20 houses. The study linked obesity to phthalates, present in many PVC items, in addition to scented items like fresheners, laundry products, and personal care products. Also linked is Bisphenol A (BPA), a known environmental obesogen that reduces the body's overall number of fat cells but which makes remaining fat cells larger. Additionally, glucose intolerance and more abdominal fat were found to be the results of obesogens in animals and the long-term effects of low-birth weight babies. The study strongly indicates that obesogens change an individual's metabolic set points for gaining weight.

Research on obesogens indicate some endocrine disrupting chemicals (EDCs) belong to this class of compounds. Bruce Blumberg, a professor of developmental and cell biology at UC Irvine, has found compelling evidence that exposure to the chemical Tributyltin (TBT), a compound used in pesticides, can trigger fat cell creation.

As several cases have confirmed, farm workers in America have unwillingly or unknowingly worked in fields that had been recently sprayed with TBT and other dangerous chemicals. Among a wide variety of health risks, farm workers may bear a disproportionate risk of exposure to such obesogens. While legislation has been enacted to require a minimum amount of time to pass before workers enter sprayed fields, the lack of legal and political power of many farm workers combined with the fact that enforcing such laws can be difficult, makes exposure to obesogens a possible threat to the livelihood of many farm workers.

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