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Through Atmospheric chemistry

His research on the asteroid impact that killed the dinosaurs led to the discovery of nuclear winter due to the major decrease in temperature. The effects of nuclear winter were re-examined in a 2006 presentation at the annual meeting of the American Geophysical Union in San Francisco, where Toon and colleagues found that even a regional nuclear war could prove deadly for a large number of people. They calculated that as few as fifty detonations of Hiroshima-size bombs could kill as many as twenty million people, although it would not produce a nuclear winter. The atmospheric effects of a regional nuclear war would last several years, and would be strongest at mid-latitudes, including the United States and Europe.

He was elected a fellow of the American Meteorological Society in 1990, and a fellow of the American Geophysical Union in 1992. He received the 2011 Roger Revelle Medal from the American Geophysical Union.

In 2022, Toon was among eight recipients of the 2022 Future of Life Award. The honor was bestowed upon Toon for "reducing the risk of nuclear war by developing and popularizing the science of nuclear winter."

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