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Phosphotransferase

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Through Protein, Enzyme and Catalysis

A−P+B↽−−⇀B−P+A

Where P is a phosphate group and A and B are the donating and accepting molecules, respectively.

Classification

Phosphotransferases are generally classified according to the acceptor molecule.

  • EC 2.7.1 Phosphotransferases with an alcohol group as acceptor
  • EC 2.7.2 Phosphotransferases with a carboxy group as acceptor
  • EC 2.7.3 Phosphotransferases with a nitrogenous group as acceptor
  • EC 2.7.4 Phosphotransferases with a phosphate group as acceptor
  • EC 2.7.9 Phosphotransferases with paired acceptors. In these reactions, a single triphosphate-nucleotide transfers two phosphates to two different acceptor molecules, resulting in a monophosphate-nucleotide and two phosphorylated products.

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