Ras superfamily
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Through Morphology (biology)
The surrounding sequence helps determine the functional specificity of the small GTPase, for example the 'Insert Loop', common to the Rho subfamily, specifically contributes to binding to effector proteins such as WASP.
In general, the Ras family is responsible for cell proliferation: Rho for cell morphology, Ran for nuclear transport, and Rab and Arf for vesicle transport.
Subfamilies and members
The following is a list of human proteins belonging to the Ras superfamily:
Unclassified:
- ARHGAP5
- DNAJC27
- GRLF1
- RASEF
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