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Rikenellaceae

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Through Gram-negative bacteria, Gastrointestinal tract and Animal

This family consists of non-motile, rod-shaped bacteria that are tolerant of bile. Most Rikenellaceae species have been identified in the gastrointestinal tract microbiomes of various animals.

Bacteria of this taxonomic family are elevated in the gut microbiomes of mice that are leptin-resistant obese and diabetic. However, Rikenellaceae bacteria are depleted in the gut microbiomes of obese American adults, leading to reduced synthesis of butyrate and disrupted metabolism.

Gut microbiomes with elevated levels of Rikenellaceae bacteria are associated with lupus and Alzheimer's disease in mice and colorectal cancer in humans.

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