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Scott A. Small

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Through Alzheimer's disease and Schizophrenia

In an interview with Mike Pesca, he mentioned that he served in the Israel Defense Forces during the 1982 Lebanon War.

Work

Small has developed high-resolution functional MRI applications that can pinpoint the areas of the hippocampus most affected by aging and disease. His lab uses this ‘anatomical biology’ approach of isolating pathogenic mechanisms to identify potential causes of these disorders and inform on drug discovery and development. To date, these mechanistic insights have led to the testing of therapeutic interventions for three hippocampal-based conditions: retromer-enhancers for Alzheimer's disease; dietary flavanols for cognitive aging; and glutamate-reducers for schizophrenia.

Small has authored more than 140 papers and is an inventor of 10 patents. He is the author of the 2021 book, Forgetting: The Benefits of Not Remembering, published by Crown/Penguin Random House (ISBN 978-0-593-13619-5).

More in Scientists, inventors, and mathematicians

National Academy of SciencesScience branch of the US National AcademiesBill ClintonPresident of the United States from 1993 to 2001American Philosophical SocietyAmerican scholarly organization and learned societyBirth nameA birth name is the name of a person given when they are born. The term may be applied to National Institutes of HealthUS government medical research agencyGermansPeople of Germany