Tight junction protein ZO-1
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Function
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell–cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Interactions
Tight junction protein 1 has been shown to interact with:
- F11 receptor,
- GJA3,
- GJA8,
- Gap junction protein, alpha 1,
- KIRREL,
- MLLT4,
- Occludin,
- TJP3, and
- Tight junction protein 2.
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