Urtė Neniškytė
Lithuanian neuroscientist (b. 1983)
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Education
Neniškytė completed her bachelor's degree in biochemistry at the Vilnius University in June, 2006. During her bachelor's program she did an internship at the European Molecular Biology Laboratory in Heidelberg, Germany. She carried out her bachelor thesis work on "Investigation of retrograde transport of heat shock protein Hsp47" at the Cell Biology and Biophysics Unit of the EMBL. Neniškytė continued with her education at the Vilnius University and was awarded with a Master of Biochemistry in 2008. Her master thesis work on "Application of microRNAs for fluorescent microscopy-based functional analysis" was done at the BioQuant institute (Center for Quantitative Analysis of Molecular and Cellular Biosystems) at Heidelberg University, Germany. She completed her PhD program in biochemistry at the St John's College of the University of Cambridge, UK in July, 2012. Her doctoral thesis subject was "Amyloid β and microglial phagocytosis". The thesis objective was to determine the role of microglial phagocytic function in neuronal loss induced by Alzheimer‘s disease peptide Aβ. By virtue of knock-out animal cell cultures and pharmacological manipulations she demonstrated that neuronal loss induced by subneurotoxic concentrations of Aβ was mediated by microglial phagocytosis.
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Career
In February 2012 Neniškytė gained a research associate position at the Department of Biochemistry of the University of Cambridge. She participated in a collaborative project with Professor Peter St George-Hyslop on the risk genes of late-onset Alzheimer’s disease and how they modulate microglial activation. Following that, she was a short- term fellow at the Neuroscience Institute of LSMU, Kaunas.
In November 2012 Neniškytė begun to work as a scientific consultant at UAB Expertus Vilnensis. She contributed to the development of automated anatomical pathology in Lithuania.
From 2013 to 2016 Neniškytė was a trainee at the EMBL under the post-doctoral Marie Skłodowska-Curie programme. She investigated the role of synaptic pruning during development, in order to identify candidate molecular tags that mediate discrimination between weak and strong synapses during circuit maturation.
Neniškytė currently works as Marie Sklodowska Curie Experienced Researcher at the Department of Neurobiology and Biophysics of Life Science Center at the Vilnius University. Her group aims to define molecular signalling pathways that drive developmental pruning of unnecessary synapses, during which immune brain cells remove unnecessary connections from the developing neuron network, creating the conditions for the formation of a structurally and functionally developed network.
Since 2006 she is a member of the Lithuanian Biochemical Society and the Lithuanian Neuroscience Association and since 2017 a board member of the Research Council of Lithuania. She is also a member of the Biochemical Society (2010), Society for Neuroscience (2013) and Young IBRO.
Awards
In recognition of her scientific achievements Neniškytė was awarded L'Oréal-UNESCO Baltic For Women in Science fellowship on 26 May, 2017. She is the first Lithuanian scientist to be presented with the award. Neniškytė is also one of the 15 laureates to receive the 2019 L'Oréal-UNESCO For Women in Science International Rising Talents award. Her other notable awards include:
International Brain Research Organization Return Home Fellowship (2017), to support the establishment of her group at the Vilnius University.
Marie Skłodowska-Curie Individual Fellowship (2016), for her project at the Vilnius University.
Marie Skłodowska-Curie Intra-European Fellowship (2012), for her project at the European Molecular Biology Laboratory.