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Gastric bypass surgery

Type of bariatric surgery

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Through Gastrointestinal tract

The operation is prescribed to treat severe obesity (defined as a body mass index greater than 40), type 2 diabetes, hypertension, obstructive sleep apnea and other comorbid conditions. Bariatric surgery is the term encompassing all of the surgical treatments for severe obesity, not just gastric bypasses, which make up only one class of such operations. The resulting weight loss, typically dramatic, markedly reduces comorbidities. The long-term mortality rate of gastric bypass patients has been shown to be reduced by up to 40%. As with all surgery, complications may occur. A study from 2005 to 2006 revealed that 15% of patients experienced complications as a result of gastric bypass, and 0.5% of patients died within six months of surgery due to complications. A meta-analysis of 174,772 participants published in The Lancet in 2021 found that bariatric surgery was associated with 59% and 30% reduction in all-cause mortality among obese adults with or without type 2 diabetes, respectively. This meta-analysis also found that median life-expectancy was 9.3 years longer for obese adults with diabetes who received bariatric surgery as compared to routine (non-surgical) care, whereas the life expectancy gain was 5.1 years longer for obese adults without diabetes.

Uses

Gastric bypass is indicated for the surgical treatment of severe obesity, a diagnosis which is made when the patient is seriously obese, has been unable to achieve satisfactory and sustained weight loss by dietary efforts and has comorbid conditions that are either life-threatening or serious impairment to the quality of life.

Before 1991, clinicians interpreted serious obesity as weighing at least 100 pounds (45 kg) more than the "ideal body weight", an actuarially determined body weight at which one was estimated to be likely to live the longest, as determined by the life-insurance industry. This criterion failed for persons of short stature.

In 1991, the National Institutes of Health (NIH) sponsored a consensus panel whose recommendations have set the current standard for consideration of surgical treatment, the body mass index (BMI). The BMI is defined as the body weight (in kilograms), divided by the square of the height (in meters). The result is expressed as a number in kilograms per square meter. In healthy adults, BMI ranges from 18.5 to 24.9, with a BMI above 30 considered obese, and a BMI less than 18.5 considered underweight.

The Consensus Panel of the National Institutes of Health (NIH) recommended the following criteria for consideration of bariatric surgery, including gastric bypass procedures:

  • people who have a BMI of 40 or higher
  • people with a BMI of 35 or higher with one or more related comorbid conditions

The Consensus Panel also emphasized the necessity of multidisciplinary care of the bariatric surgical patient by a team of physicians and therapists to manage associated comorbidities and nutrition, physical activity, behavior and psychological needs. The surgical procedure is best regarded as a tool that enables the patient to alter lifestyle and eating habits, and to achieve effective and permanent management of obesity and eating behavior.

Since 1991, major developments in the field of bariatric surgery, particularly laparoscopy, have outdated some of the conclusions of the NIH panel. In 2004 the American Society for Bariatric Surgery (ASBS) sponsored a consensus conference which updated the evidence and the conclusions of the NIH panel. This conference, composed of physicians and scientists of both surgical and non-surgical disciplines, reached several conclusions, including:

  • bariatric surgery is the most effective treatment for severe obesity
  • gastric bypass is one of four types of operations for severe obesity
  • laparoscopic surgery is equally effective and as safe as open surgery
  • patients should undergo comprehensive preoperative evaluation and have multi-disciplinary support for optimum outcome

In recent comparisons with sleeve gastrectomy, gastric bypass has shown slightly better outcomes in diabetes remission and weight maintenance. According to a 2021 evidence update, Roux-en-Y gastric bypass (RYGB) patients were more likely to maintain weight loss over five years, with a reduced relapse rate in Type 2 diabetes. However, RYGB was associated with a higher frequency of follow-up surgeries and hospitalizations due to complications.

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