Hyperuricosuria

Medications that may contribute to the cure or amelioration of hyperuricosuria include allopurinol which acts by inhibiting xanthine oxidase and reducing uric acid production. Hyperuricosuria may be a medical sign of:

• Gout (very common)
• Kidney stones of uric acid (uric acid nephrolithiasis)
• Acute uric acid nephropathy
• Acute kidney failure
• Tumor lysis syndrome
• Fanconi syndrome
• Dent's disease (very rare)

Classification

Acute hyperuricosuria is a common complication of tumor lysis syndrome. This syndrome appears not to contribute to gout and to uric acid nephrolithiasis, which is evidence that these two conditions have chronic, not acute, causes.

Chronic hyperuricosuria is associated with gout and uric acid nephrolithiasis. However, both conditions can occur in the absence of hyperuricosuria. Treatment of gout with uricosuric drugs can lead to uric acid nephrolithiasis.