Lutheran antigen system
Human blood group system
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Related on Lably
Through Human blood group systems, Fetus and Allele
The phenotypes Lu(a+b−) and Lu(a+b+) are found at various frequencies within populations. The Lu(a−b+) phenotype is the most common in all populations, whereas the Lu(a−b−) phenotype is uncommon. Though present in the fetus, it is seldom the cause of erythroblastosis fetalis or of transfusion reactions.
Clinical diagnostic
Clinical testing in patient care for Lutheran antigens follows published minimum quality and operational requirements, similar to red cell genotyping for any of the other recognized blood group systems. Molecular analysis can identify gene variants (alleles) that may affect Lutheran antigens expression on the red cell membrane.
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