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Saccharopolyspora erythraea

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Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. Cytochrome P450 eryF (CYP107A1) originally from the bacterium is responsible for the biosynthesis of the antibiotic by C6-hydroxylation of the macrolide 6-deoxyerythronolide B.

Small non-coding RNAs have been suggested to be involved in regulation of the secondary metabolite biosynthesis.

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