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CHARGE study

Childhood autism risk factor study

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Research

A number of peer-reviewed papers have been produced as a result of this study. They have concluded that:

  • There is an association between living near a freeway and risk of autism.
  • No association was found between blood levels of mercury and autism among a group of children studied at two-to-five years of age.
  • There is an association between exposure to traffic-related air pollution and autism risk.
  • There may be a causative link between both exposure to air pollution, a variant in the MET receptor tyrosine kinase gene and risk of autism.
  • Maternal use of folic acid supplements may be associated with a decreased risk of autism. However, the researchers cautioned that further research is warranted to confirm or refute this finding.
  • Maternal fever during pregnancy is associated with an increased risk of autism in her child.
  • Gastrointestinal problems are significantly more common in children with autism than children without autism.

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