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Effects of meditation

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Through Awareness, Attention and Attention span

Since the 1950s, hundreds of studies on meditation have been conducted, but many of the early studies were flawed and thus yielded unreliable results. Another major review article also cautioned about possible misinformation and misinterpretation of data related to the subject. Contemporary studies have attempted to address many of these flaws by employing randomized controlled trials, active control groups, and more rigorous methodological standards, with several meta-analyses of clinical studies also examining the potential mental and physical health effects of meditation across different populations.

An extensive review of 44 meta-analyses, encompassing 336 randomized controlled trials and over 30,000 participants, systematically evaluated the empirical status of mindfulness-based interventions. The authors concluded that these interventions demonstrate substantial transdiagnostic potential, while also identifying ways in which the evidence base could be further strengthened. Further, recent (2026) meta-analyses indicate that second-generation mindfulness-based interventions that incorporate compassion-based practices may be especially beneficial for clinical populations.

Some researchers have questioned the validity of self-reported mindfulness, suggesting that increases observed during interventions may be an artefact rather than an intervention effect, as similar increases have also been found in control groups. Others have stated that individual differences may exist in terms of who could benefit from mindfulness. However, more recent meta-analysis of randomized studies indicate that mindfulness practices can also bring about changes in objectively measured outcomes, including performance-based measures of cognitive functioning, physiological measures such as blood pressure, measures of brain function, and changes in biomarkers.

Effects of mindfulness meditation

Several systematic reviews and meta-analyses show that mindfulness meditation has mental health benefits, including reductions in depression symptoms, improvements in mood, strengthening of stress-resilience, and attentional control. Mindfulness interventions also appear promising for managing depression in youth. Mindfulness meditation is useful for managing stress, anxiety, and also appears to be effective in treating substance use disorders. In 2016, Hilton and colleagues published a meta-analysis of 30 randomized controlled trials, found high-quality evidence for improvement in depressive symptoms. Other reviews have concluded that mindfulness meditation can enhance the psychological functioning of breast cancer survivors, is effective for people with eating disorders and may also be effective in treating psychosis.

Studies have also shown that rumination and worry contribute to mental illnesses such as depression and anxiety, and mindfulness-based interventions are effective in the reduction of worry. Some studies suggest that mindfulness meditation contributes to a more coherent and healthy sense of self and identity when considering aspects such as a sense of responsibility, authenticity, compassion, self-acceptance, and character.

Brain mechanisms

The analgesic effect of mindfulness meditation may involve multiple brain mechanisms, of which chronic pain is shown to have a slight decrease when performing meditation. Current research demonstrates a lack of high-quality data to support a strong case for clinical prescription of meditation, however future research may further change our understanding of chronic pain treatment and mindfulness, but there are too few studies to allow conclusions about its effects on chronic pain.

Changes in the brain

Mindfulness meditation alters the brain, leading to a heightened ability to improve emotions. In an 8-week mindfulness meditation study, Gotink et al. results showed activity in the amygdala, insula, cingulate cortex, and hippocampus to decrease. Short-term brain changes such as these are correlated to effects seen in people who have practiced mindfulness over longer periods such as months or years. Another meta-analysis found preliminary evidence for effects in the prefrontal cortex and other brain regions associated with body awareness. However, these results should be interpreted with caution as funnel plots indicate that publication bias is an issue in meditation research. A 2016 review using 78 functional neuroimaging studies suggests that different meditation styles result in different brain activity. While other studies have found structural changes in the brain may occur, most studies have utilized weak methodology.

Attention and mindfulness

Attention networks and mindfulness meditation

Psychological and Buddhist conceptualizations of mindfulness both highlight awareness and attention training as key components in which levels of mindfulness can be cultivated with the practice of mindfulness meditation. Focused attention meditation (FAM) and open monitoring meditation (OMM) are distinct types of mindfulness meditation; FAM refers to the practice of intently maintaining focus on one object, whereas OMM is the progression of general awareness of one's surroundings while regulating thoughts. Some forms of Buddhist mindfulness meditation may lead to greater cognitive flexibility.

In an active randomized controlled study completed in 2019, participants who practiced mindfulness meditation demonstrated a greater improvement in awareness and attention than participants in the active control condition. Alpha wave neural oscillation power (which is usually associated with an alert resting state) has been shown to be increased by mindfulness in both healthy subjects and patients.

Sustained attention

Tasks of sustained attention relate to vigilance and the preparedness that aids in completing a particular task goal. Psychological research into the relationship between mindfulness meditation and the sustained attention network has revealed the following:

  • In a continuous performance task an association was found between higher dispositional mindfulness and more stable maintenance of sustained attention.
  • In an electroencephalography study, the attentional blink effect was reduced, and P3b ERP amplitude decreased in a group of participants who completed a mindfulness retreat. The incidence of reduced attentional blink effect relates to an increase in the detectability of a second target.
  • A greater degree of attentional resources may also be reflected in faster response times in task performance, as was found for participants with higher levels of mindfulness experience.

Selective attention

  • Selective attention, linked with the orientation network, selects the relevant stimuli to attend to.
  • Performance in the ability to limit attention to potential sensory inputs (i.e., selective attention) was found to be higher following the completion of an eight-week MBSR course, compared to a one-month retreat and control group (with no mindfulness training). The ANT task is a general applicable task designed to test the three attention networks, in which participants are required to determine the direction of a central arrow on a computer screen. Efficiency in orienting that represent the capacity to attend to stimuli selectively was calculated by examining changes in the reaction time that accompanied cues indicating where the target occurred relative to the aid of no cues.
  • Meditation experience correlates negatively with reaction times on an Eriksen flanker task measuring responses to global and local figures. Similar findings have been observed for correlations between mindfulness experience and an orienting score of response times taken from Attention Network Task performance.
  • Participants who engaged in the Meditation Breath Attention Score exercise performed better on anagram tasks and reported greater focused attention on this task compared to those who did not undergo this exercise.

Executive control attention

  • Executive control attention includes functions of inhibiting the conscious processing of distracting information. In the context of mindful meditation, distracting information relates to attention-grabbing mental events, such as thoughts related to the future or past.
  • More than one study has reported findings of a reduced Stroop effect following mindfulness meditation training. The Stroop effect indexes interference created by having words printed in a color different from the read semantic meaning, e.g., green printed in red. However, the findings for this task are not consistently found. For instance the MBSR may differ to how mindful one becomes relative to a person who is already high in trait mindfulness.
  • Using the Attention Network Task, a version of the Eriksen flanker task, it was found that error scores that indicate executive control performance were reduced in experienced meditators and following a brief five-session mindfulness training program.
  • A neuroimaging study supports behavioral research findings that higher levels of mindfulness are associated with greater proficiency in inhibiting distracting information. A greater activation of the rostral anterior cingulate cortex (ACC) was shown for mindfulness meditators than matched controls.
  • Participants with at least 6 years of experience meditating performed better on the Stroop Test than participants without experience meditating. The group of meditators also had lower reaction times during this test than the group of non-meditators.
  • Following a Stroop test, reduced amplitude of the P300 ERP component was found for a meditation group relative to control participants. This was taken to signify that mindfulness meditation improves executive control functions of attention. An increased amplitude in the N2 ERP component was also observed in the mindfulness meditation group, which was thought to reflect more efficient perceptual discrimination in earlier stages of perceptual processing.

Emotion regulation and mindfulness

Research shows meditation practices lead to greater emotional regulation abilities. Mindfulness can help people become more aware of thoughts in the present moment, and this increased self-awareness leads to better processing and control over one's responses to surroundings or circumstances.

Positive effects of this heightened awareness include a greater sense of empathy for others, increased positive thinking patterns, and reduced anxiety. Reductions in rumination also have been found following mindfulness meditation practice, contributing to the development of positive thinking and emotional well-being.

Evidence of mindfulness and emotion regulation outcomes

Emotional reactivity can be measured and reflected in brain regions related to the production of emotions. It can also be reflected in tests of attentional performance, indexed in poorer performance in attention-related tasks. The regulation of emotional reactivity as initiated by attentional control capacities can be taxing to performance, as attentional resources are limited.

  • Patients with social anxiety disorder (SAD) exhibited reduced amygdala activation in response to negative self-beliefs following an MBSR intervention program that involves mindfulness meditation practice.
  • The LPP ERP component indexes arousal and is larger in amplitude for emotionally salient stimuli relative to neutral. Individuals higher in trait mindfulness showed lower LPP responses to high arousal unpleasant images. These findings suggest that individuals with higher trait mindfulness were better able to regulate emotional reactivity to emotionally evocative stimuli.
  • Participants who completed a seven-week mindfulness training program demonstrated a reduction in a measure of emotional interference (measured as slower response times following the presentation of emotion relative to neutral pictures). This suggests a reduction in emotional interference.
  • Following an MBSR intervention, decreases in social anxiety symptom severity and increases in bilateral parietal cortex neural correlates were found. This is thought to reflect the increased employment of inhibitory attentional control capacities to regulate emotions.
  • Participants who engaged in emotion-focus meditation and breathing meditation exhibited a delayed emotional response to negatively valenced film stimuli compared to participants who did not engage in any type of meditation.

Controversies in mindful emotion regulation

It is debated as to whether top-down executive control regions such as the dorsolateral prefrontal cortex (DLPFC), are required or not to inhibit reactivity of the amygdala activation related to the production of evoked emotional responses. Arguably, an initial increase in activation of executive control regions developed during mindfulness training may lessen with increasing mindfulness expertise.

Furthermore, current research data is inconclusive and incomplete in linking the positive effects of mindful meditation with a variety of reported positive effects. Additional high-fidelity studies are needed before a complete understanding of the full effects of mindfulness can be reached.

Stress reduction

Research has shown stress reduction benefits from mindfulness. A 2019 study tested the effects of meditation on the psychological well-being, work stress, and blood pressure of employees working in the United Kingdom. One group of participants was instructed to meditate once a day using a smartphone mindfulness app, while the control group did not engage in meditation. Measurements of well-being, stress, and perceived workplace support were taken for both groups before the intervention and then again after four months. Based on self-report questionnaires, the participants who engaged in meditation showed a significant increase in psychological well-being and perceived workplace support. The meditators also reported a significant decrease in anxiety and stress levels.

Another study conducted to understand the association between mindfulness, perceived stress, and work engagement indicated that mindfulness was associated with lower perceived stress and higher work engagement.

An additional study from 2021 looking at the effect of centering meditation intervention on stress levels of college students saw a statistically significant improvement in stress and mindfulness levels over time. Inclusive of this was the finding that it helped reduce stress and the variance of that stress on a participant-to-participant basis.

Other research shows decreased stress levels in people who engage in meditation after shorter periods of time as well. Evidence of significant stress reduction was found after only three weeks of meditation intervention. Brief, daily meditation sessions can alter one's behavioral response to stressors, improving coping mechanisms and decreasing the adverse impact caused by stress. A study from 2016 examined anxiety and emotional states of naive meditators before and after a seven-day meditation retreat in Thailand. Results displayed a significant reduction in perceived stress after this traditional Buddhist meditation retreat.

Cancer diagnosis and treatment often comes with psychological complications; as an example, rates of psychological distress in breast cancer patients in China was a staggering 49%. A meta-analysis of 869 studies saw that Mindfulness-based stress reduction resulted in significant decreases of anxiety and depression levels in cancer patients.

Insomnia and sleep

Chronic insomnia is often associated with anxious hyperarousal and frustration over the inability to sleep. Mindfulness has been shown to reduce insomnia and improve sleep quality, although self-reported measures show larger effects than objective measures.

A 2008 study looked at the combination of meditation and cognitive behavioral therapy in treating those meeting the diagnostic criteria for psychophysiological insomnia. Results after the 6-week intervention showed statistically significant improvements in pre-sleep arousal, sleep-related distress, and insomnia.

Sleep disturbance is a common symptom of cancer that many patients face, with incidence rates ranging anywhere from 30 - 90%. A 2023 meta-analysis looking at the relationship between meditation and cancer-related sleep disturbance saw significant immediate effects in patients on self-reported sleep disturbance levels.

Meditation And Cancer

Cancer itself and the treatment patients go through often comes with varying side effects including fatigue, nausea, sleep disturbance, pain, and others. Over the past few decades, the connection between meditation and its effect on cancer has been a topic of interest for researchers. Mindfulness meditation, in particular, has been shown to influence health outcomes associated with cancer diagnosis and treatment, including pain, mental health and sleep disturbance, which have susceptibility to play off of one another.

Pain

Pain is a common side effect of cancer patients, with 30-50% of patients experiencing moderate to severe levels. Mindfulness-based cognitive therapy was found to garner statistically significant effects in regards to self-reported pain levels in cancer patients after 8 weeks. Inclusive of this was another finding that pain severity may be lowered through mindfulness-based interventions. Research saw that mindfulness meditation may additionally be effective in pain management as the patient's report of the pain can be lessened through diverting their attention away from the symptoms, thus increasing pain tolerance. Though studies have brought about significant evidence of meditation's effect on pain management, scholars believe that it should not be used as a mainstay treatment for cancer pain without further research.

Mental Health

Cancer diagnosis and treatment often comes with psychological complications; as an example, rates of psychological distress in breast cancer patients in China was a staggering 49%. Armed with this information, researchers began to look into interventions to help alleviate the mental suffering of patients, including meditation. When regarding cancer-related effects on mental health, a meta-analysis of 869 studies saw that Mindfulness-based stress reduction resulted in lower anxiety and depression levels in cancer patients as well as improvement in physical functioning. In a review of 29 randomized controlled trials looking into nonpharmacological mediations for impairment of cognition relating to cancer, meditation was found to be the best option when compared to other interventions including yoga, acupuncture, and cognitive training.

Sleep Disturbance

Sleep disturbance is a common symptom of cancer that many patients face, with incidence rates ranging anywhere from 30 - 90%. Disturbances in sleep have been found to result in other consequences such as stress, fatigue, and cognitive impairment. Research has been conducted on the connection between meditation and sleep disturbance to see if it is deemed effective as an intervention. A meta analysis of 56 studies saw mindfulness to result in significant immediate effects on sleep disturbance. Additional results yielded statistically significant short-term effects on sleep in patients when compared to education and breath control. Sleep disturbance was found to be relieved in patients who underwent mindfulness-based intervention. When accounting for longevity, a meta-analysis found the effects of mindfulness on sleep to last around 6 months.

Future directions

A large part of mindfulness research is dependent on technology. As new technology develops, new imaging techniques will become helpful in this field. Real-time fMRI might give immediate feedback and guide participants through the programs. It could also be used to train and evaluate mental states more easily during meditation itself.

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