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Foundations of statistics

Concepts underlying statistical methods

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Through Mathematics, Statistical inference and Estimation

Different statistical foundations may provide different, contrasting perspectives on the analysis and interpretation of data, and some of these contrasts have been subject to centuries of debate. Examples include the Bayesian inference versus frequentist inference; the distinction between Fisher's significance testing and the Neyman-Pearson hypothesis testing; and whether the likelihood principle holds.

Certain frameworks may be preferred for specific applications, such as the use of Bayesian methods in fitting complex ecological models.

Bandyopadhyay & Forster identify four statistical paradigms: classical statistics (error statistics), Bayesian statistics, likelihood-based statistics, and information-based statistics using the Akaike Information Criterion. More recently, Judea Pearl reintroduced formal mathematics by attributing causality in statistical systems that addressed the fundamental limitations of both Bayesian and Neyman-Pearson methods, as discussed in his book Causality.

Fisher's "significance testing" vs. Neyman–Pearson "hypothesis testing"

During the 20th century, the development of classical statistics led to the emergence of two competing foundations for inductive statistical testing. The merits of these models were extensively debated. While a hybrid of the two methods is widely taught and used, the philosophical questions raised in the debate have not been resolved..

Significance testing

Fisher popularized significance testing with Statistical Methods for Research Workers, published in 1925, and The Design of Experiments, published in 1935. Fisher was motivated to obtain scientific experimental results without the explicit influence of prior opinion. The significance test is a probabilistic version of modus tollens, a classic form of deductive inference. The significance test might be simplistically stated, "If the evidence is sufficiently discordant with the hypothesis, reject the hypothesis". In application, a statistic is calculated from the experimental data, and the probability of exceeding that statistic under a default or 'null' model is compared to a threshold. The threshold (the numeric version of "sufficiently discordant") is arbitrary (usually decided by convention). A common application of the method is deciding whether a treatment has a reportable effect based on a comparative experiment. The null hypothesis then corresponds to the model with no treatment effect, implying the treated and the controls come from the same population. Statistical significance is a measure of probability, not practical importance. It can be regarded as a requirement placed on statistical signal/noise. Note that the test cannot prove the hypothesis (of no treatment effect), but only provide more or less evidence against it. The method is based on the formulation of an imaginary infinite population (i.e. a specified statistical model) corresponding to the null hypothesis.

The Fisherian significance test involves only one hypothesis, but the choice of test statistic requires at least a feeling for relevant directions of deviation from the hypothesis model. Historically, the result of the test was either to reject the hypothesis or not, whereas nowadays the probability of observing the test results assuming the hypothesis can be calculated with the aid of computers, which was impossible in Fisher's day. This probability, known as the p-value, allows for a more precise assessment of the significance of the result.

Hypothesis testing

Neyman & Pearson collaborated on a different, but related, problem – selecting among competing hypotheses based on the experimental evidence alone. Of their joint papers, the most cited is from 1933. The famous result of that paper is the Neyman–Pearson lemma. The lemma says that a ratio of probabilities is an excellent criterion for selecting a hypothesis (with the threshold for comparison being arbitrary). The paper proved an optimality of Student's t-test (one of the significance tests). Neyman expressed the opinion that hypothesis testing was a generalization of and an improvement on significance testing. The rationale for their methods is found in their joint papers.

Hypothesis testing requires multiple hypotheses. A hypothesis is always selected, a multiple choice. A lack of evidence is not an immediate consideration. The method is based on the assumption of repeated sampling of the same population (the classical frequentist assumption), although Fisher criticized this assumption (Rubin, 2020).

Grounds of disagreement

The length of the dispute allowed the debate of a wide range of issues regarded as foundational to statistics.

An example exchange from 1955–1956

Fisher's attack[12]

Repeated sampling of the same population

Type II errors

  • Which result from an alternative hypothesis

Inductive behavior

Neyman's rebuttal[13]

Fisher's attack on inductive behavior has been largely successful because he selected the field of battle. While operational decisions are routinely made on a variety of criteria (such as cost), scientific conclusions from experimentation are typically made based on probability alone. Fisher's theory of fiduciary inference is flawed

  • Paradoxes are common

A purely probabilistic theory of tests requires an alternative hypothesis. Fisher's attacks on Type II errors have faded with time. In the intervening years, statistics have separated the exploratory from the confirmatory. In the current environment, the concept of Type II errors are used in power calculations for confirmatory hypothesis tests' sample size determination.

Discussion

Fisher's attack based on frequentist probability failed but was not without result. He identified a specific case (2×2 table) where the two schools of testing reached different results. This case is one of several that are still troubling. Commentators believe that the "right" answer is context-dependent. Fiducial probability has not fared well, being virtually without advocates, while frequentist probability remains a mainstream interpretation.

Fisher's attack on inductive behavior has been largely successful because he selected the field of battle. While ''operational decisions'' are routinely made on a variety of criteria (such as cost), ''scientific conclusions'' from experimentation are typically made based on probability alone.

In this exchange, Fisher also discussed the requirements for inductive inference, with specific criticism of cost functions penalizing faulty judgments. Neyman countered that Gauss and Laplace used them. This exchange of arguments occurred 15 years after textbooks began teaching a hybrid theory of statistical testing.

Fisher and Neyman were in disagreement about the foundations of statistics (although united in vehement opposition to the Bayesian view):

  • The interpretation of probability
    • The disagreement between Fisher's inductive reasoning and Neyman's inductive behavior contained elements of the Bayesian-Frequentist divide. Fisher was willing to revise his opinion (reaching a provisional conclusion) based on calculated probability, while Neyman was more inclined to adjust his observable behavior (making a decision) based on computed costs.
  • The appropriate formulation of scientific questions, with a particular focus on modelling
  • Whether it is justifiable to reject a hypothesis based on a low probability without knowing the probability of an alternative
  • Whether a hypothesis could ever be accepted based solely on data
    • In mathematics, deduction proves, while counter-examples disprove.
    • In the Popperian philosophy of science, progress is made when theories are disproven.
  • Subjectivity: While Fisher and Neyman struggled to minimize subjectivity, both acknowledged the importance of "good judgment". Each accused the other of subjectivity.
    • Fisher subjectively selected the null hypothesis.
    • Neyman-Pearson subjectively determined the criterion for selection (which was not limited to probability).
    • Both subjectively established numeric thresholds.

Fisher and Neyman were separated by attitudes and perhaps language. Fisher was a scientist and an intuitive mathematician. Inductive reasoning was natural. Neyman was a rigorous mathematician. He was convinced by deductive reasoning rather than by a probability calculation based on an experiment. Thus there was an underlying clash between applied and theoretical (between science and mathematics).

Neyman, who had occupied the same building in England as Fisher, accepted a position on the West coast of the United States of America in 1938. His move effectively ended his collaboration with Pearson and their development of hypothesis testing. Further development was continued by others.

Textbooks provided a hybrid version of significance and hypothesis testing by 1940. None of the principals had any known personal involvement in the further development of the hybrid taught in introductory statistics today.

Statistics later developed in different directions including decision theory (and possibly game theory), Bayesian statistics, exploratory data analysis, robust statistics, and nonparametric statistics. Neyman–Pearson hypothesis testing contributed strongly to decision theory which is very heavily used (in statistical quality control for example). Hypothesis testing readily generalized to accept prior probabilities which gave it a Bayesian flavor.

Neyman–Pearson hypothesis testing has become an abstract mathematical subject taught in post-graduate statistics, while most of what is taught to under-graduates and used under the banner of hypothesis testing is from Fisher.

Contemporary opinion

The hybrid of the two competing schools of testing can be viewed differently: as the imperfect union of two mathematically complementary ideas or as the fundamentally flawed union of philosophically incompatible ideas. Fisher enjoyed some philosophical advantage, while Neyman & Pearson employed the more rigorous mathematics. Hypothesis testing is controversial among some users, but the most popular alternative (confidence intervals) is based on the same mathematics.

The history of the development left testing without a single citable authoritative source for the hybrid theory that reflects common statistical practice. The merged terminology is also somewhat inconsistent. There is strong empirical evidence that the graduates (and instructors) of an introductory statistics class have a weak understanding of the meaning of hypothesis testing.

Summary

  • The interpretation of probability has not been resolved (but the fiducial probability is an orphan).
  • Neither test method has been rejected. Both are heavily used for different purposes.
  • Texts have merged the two test methods under the term hypothesis testing.
    • Mathematicians claim (with some exceptions) that significance tests are a special case of hypothesis tests.
    • Others treat the problems and methods as distinct (or incompatible).
  • The dispute has adversely affected statistical education.

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