Polyene antimycotic
- 1 min read
- 3 chapters
Related on Lably
Structures
Their chemical structures feature a large ring of atoms (in essence, a cyclic ester ring) containing multiple conjugated carbon-carbon double bonds (hence polyene) on one side of the ring and multiple hydroxyl groups bonded to the other side of the ring. Their structures also often have a D-mycosamine (a type of amino-glycoside) group bonded to the molecule. The series of conjugated double bonds typically absorbs strongly in the ultraviolet-visible region of the electromagnetic spectrum, often resulting in the polyene antibiotics having a yellow color.
Sign in to keep reading
2 more chapters are free with a Lably account.
Biosynthesis
The natural route to synthesis includes polyketide synthase components.
Other examples of polyenes
- Rimocidin
- Filipin
- Candicin
- Hamycin
- Perimycin
- Dermostatin

