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IARC group 3

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Through Mixture, Hazard and Risk

The IARC Monographs on which this list is based assess the hazard linked to the agents, they do not assess the cancer risk of the agents. The list is up-to-date as of January 2024.

Agents and groups of agents

A

B

  • 11H-Benz[bc]aceanthrylene
  • Benz[l]aceanthrylene
  • Benz[a]acridine
  • Benz[c]acridine
  • Benzo[g]chrysene
  • Benzo[a]fluoranthene
  • Benzo[ghi]fluoranthene
  • Benzo[a]fluorene
  • Benzo[b]fluorene
  • Benzo[c]fluorene
  • Benzo[ghi]perylene
  • Benzo[e]pyrene
  • p-Benzoquinone dioxime
  • Benzoyl peroxide
  • Benzyl acetate
  • Bis(1-aziridinyl)morpholinophosphine sulfide
  • Bis(2-chloroethyl)ether
  • 1,2-Bis(chloromethoxy)ethane
  • 1,4-Bis(chloromethoxymethyl)benzene
  • Bis(2-chloro-1-methylethyl)ether
  • Bis(2,3-epoxycyclopentyl)ether
  • Bisphenol A diglycidyl ether (Aralditeâ)
  • Bisulfites
  • Blue VRS
  • Brilliant Blue FCF, disodium salt
  • Bromochloroacetonitrile
  • Bromoethane
  • Bromoform
  • 2-Butoxyethanol
  • 1-tert-Butoxy-2-propanol
  • n-Butyl acrylate
  • Butylated hydroxytoluene (BHT)
  • Butyl benzyl phthalate
  • gamma-Butyrolactone

C

  • Caffeine
  • Cantharidin
  • Caprolactam
  • Captan
  • Carbaryl
  • 3-Carbethoxypsoralen
  • Carmoisine
  • Carrageenan
  • Chloramine
  • Chlordimeform
  • Chlorinated drinking water
  • Chloroacetonitrile
  • Chlorobenzilate
  • Chlorodibromomethane
  • Chlorodifluoromethane
  • Chloroethane
  • Chlorofluoromethane
  • 4-Chloro-meta-phenylenediamine
  • Chloronitrobenzenes
  • Chloropropham
  • Chloroquine
  • 5-Chloro-ortho-toluidine
  • 2-Chloro-1,1,1-trifluoroethane
  • Cholesterol
  • Chromium(III) compounds
  • Chromium, metallic
  • Chrysoidine
  • CI Acid Orange 3
  • Cimetidine
  • Cinnamyl anthranilate
  • CI Pigment Red 3
  • Citrinin
  • Clofibrate
  • Clomiphene citrate
  • Coal dust
  • Cobalt(II) sulfide
  • Cobalt(II,III) oxide
    • Other cobalt(II) compounds (not including soluble cobalt(II) salts, cobalt(II) oxide, cobalt(II,III) oxide, and cobalt(II) sulfde)
  • Continuous glass filament
  • Copper 8-hydroxyquinoline
  • Coronene
  • Coumarin
  • m-Cresidine
  • Cyclamates
  • Cyclochlorotine
  • Cyclohexanone
  • 4H-Cyclopenta[def]chrysene
  • 5,6-Cyclopenteno-1,2-benzanthracene

D

  • D & C Red No. 9
  • Dapsone
  • Decabromodiphenyl oxide
  • Deltamethrin
  • Diacetylaminoazotoluene
  • Diallate
  • 1,2-Diamino-4-nitrobenzene
  • 1,4-Diamino-2-nitrobenzene
  • 2,5-Diaminotoluene
  • Diazepam
  • Diazomethane
  • Dibenz[a,c]anthracene
  • Dibenz[a,j]anthracene
  • Dibenzo-p-dioxin
  • Dibenzo[a,e]fluoranthene
  • 13H-Dibenzo[a,g]fluorene
  • Dibenzo[h,rst]pentaphene
  • Dibenzo[a,e]pyrene
  • Dibenzo[e,l]pyrene
  • Dichloroacetonitrile
  • Dichloroacetylene
  • m-Dichlorobenzene
  • o-Dichlorobenzene
  • trans-1,4-Dichlorobutene
  • 2,6-Dichloro-p-phenylenediamine
  • Dicofol
  • Didanosine
  • Di(2-ethylhexyl) adipate
  • Di(2-ethylhexyl) phthalate
  • N,N'-Diethylthiourea
  • 1,2-Dihydroaceanthrylene
  • Dihydroxymethylfuratrizine
  • Dimethoxane
  • 3,3'-Dimethoxybenzidine-4,4'-diisocyanate
  • p-Dimethylaminoazobenzenediazo sodium sulfonate
  • 4,4'-Dimethylangelicin plus ultraviolet A radiation
  • 4,5'-Dimethylangelicin plus ultraviolet A radiation
  • N,N-Dimethylaniline
  • 1,4-Dimethylphenanthrene
  • 3,5-Dinitrotoluene
  • Dinitrosopentamethylenetetramine
  • 2,4'-Diphenyldiamine
  • Disperse Yellow 3
  • Disulfiram
  • Dithranol
  • Doxefazepam
  • Doxylamine succinate
  • Droloxifene
  • Dulcin

E–G

H–L

M

  • Madder root (Rubia tinctorum)
  • Magnetic fields (static)
  • Malachite green
  • Maleic hydrazide
  • Malonaldehyde
  • Maneb
  • Mannomustine dihydrochloride
  • Medphalan
  • 6-Mercaptopurine
  • Mercury and inorganic mercury compounds
  • Metabisulfites
  • Methimazole
  • Methotrexate
  • Methoxychlor
  • 5-Methylangelicin
  • Methyl bromide
  • Methyl tert-butyl ether
  • Methyl carbamate
  • Methyl chloride
  • 1-Methylchrysene
  • 2-Methylchrysene
  • 3-Methylchrysene
  • 4-Methylchrysene
  • 6-Methylchrysene
  • N-Methyl-N,4-dinitrosoaniline
  • 4,4'-Methylene bis(N,N-dimethyl)benzenamine
  • 4,4'-Methylenediphenyl diisocyanate
  • 2-Methylfluoranthene
  • 3-Methylfluoranthene
  • Methylglyoxal
  • Methyl iodide
  • Methyl methacrylate
  • Methyl parathion
  • 1-Methylphenanthrene
  • 7-Methylpyrido[3,4-c]psoralen
  • Methyl red
  • Methyl selenac
  • Microcystis extracts
  • Modacrylic fibres
  • Monuron
  • Morpholine
  • Musk ambrette
  • Musk xylene

N–O

  • 1,5-Naphthalenediamine
  • 1,5-Naphthalene diisocyanate
  • Naphtho[1,2-b]fluoranthene
  • Naphtho[2,1-a]fluoranthene
  • Naphtho[2,3-e]pyrene
  • 1-Naphthylamine
  • 1-Naphthylthiourea (ANTU)
  • Nithiazide
  • 5-Nitro-ortho-anisidine
  • 9-Nitroanthracene
  • 7-Nitrobenz[a]anthracene
  • 6-Nitrobenzo[a]pyrene
  • 4-Nitrobiphenyl
  • 3-Nitrofluoranthene
  • Nitrofural (Nitrofurazone)
  • Nitrofurantoin
  • 1-Nitronaphthalene
  • 2-Nitronaphthalene
  • 3-Nitroperylene
  • 2-Nitropyrene
  • N'-Nitrosoanabasine
  • N'-Nitrosoanatabine
  • N-Nitrosodiphenylamine
  • para-Nitrosodiphenylamine
  • N-Nitrosofolic acid
  • N-Nitrosoguvacine
  • N-Nitrosoguvacoline
  • N-Nitrosohydroxyproline
  • 3-(N-Nitrosomethylamino)propionaldehyde
  • 4-(N-Nitrosomethylamino)-4-(3-pyridyl)-1-butanal (NNA)
  • N-Nitrosoproline
  • Nitrotoluenes
  • 5-Nitro-ortho-toluidine
  • Nitrovin
  • Nodularins
  • Nylon 6
  • Oestradiol mustard
  • Opisthorchis felineus (infection with)
  • Orange I
  • Orange G
  • Oxyphenbutazone

P

Q–R

  • Quercetin
  • para-Quinone
  • Quintozene (Pentachloronitrobenzene)
  • Reserpine
  • Resorcinol
  • Retrorsine
  • Rhodamine B
  • Rhodamine 6G
  • Rifampicin
  • Ripazepam
  • Rock (stone) wool
  • Rugulosin

S

  • Saccharated iron oxide
  • Saccharin and its salts
  • Scarlet Red
  • Schistosoma mansoni (infection with)
  • Selenium and selenium compounds
  • Semicarbazide hydrochloride
  • Seneciphylline
  • Senkirkine
  • Sepiolite
  • Shikimic acid
  • Silica, amorphous
  • Simazine
  • Slag wool
  • Sodium chlorite
  • Sodium diethyldithiocarbamate
  • Spironolactone
  • Styrene-acrylonitrile copolymers
  • Styrene-butadiene copolymers
  • Succinic anhydride
  • Sudan I
  • Sudan II
  • Sudan III
  • Sudan Brown RR
  • Sudan Red 7B
  • Sulfafurazole (Sulfisoxazole)
  • Sulfamethazine
  • Sulfamethoxazole
  • Sulfites
  • Sulfur dioxide
  • Sunset Yellow FCF
  • Surgical implants
  • Surgical implants, female breast reconstruction, silicone
  • Symphytine

T

  • Talc, not containing asbestiform fibres
  • Tannic acid and tannins
  • Temazepam
  • 2,2',5,5'-Tetrachlorobenzidine
  • Tetrakis(hydroxymethyl)phosphonium salts
  • Theobromine
  • Theophylline
  • Thiourea
  • Thiram
  • Toluene
  • Toremifene
  • Toxins derived from Fusarium graminearum, F. culmorum and F. crookwellense (zearalenone, deoxynivalenol, nivalenol, and fusarenone X)
  • Toxins derived from Fusarium sporotrichioides
  • Trichlorfon
  • Trichloroacetonitrile
  • 1,1,2-Trichloroethane
  • Triethanolamine
  • Triethylene glycol diglycidyl ether
  • Trifluralin
  • 4,4',6-Trimethylangelicin plus ultraviolet A radiation
  • 2,4,5-Trimethylaniline
  • 2,4,6-Trimethylaniline
  • 4,5',8-Trimethylpsoralen
  • 2,4,6-Trinitrotoluene
  • Triphenylene
  • Tris(aziridinyl)-para-benzoquinone (Triaziquone)
  • Tris(1-aziridinyl)phosphine oxide
  • 2,4,6-Tris(1-aziridinyl)-s-triazine
  • Tris(2-chloroethyl) phosphate
  • 1,2,3-Tris(chloromethoxy)propane
  • Tris(2-methyl-1-aziridinyl)phosphine oxide

U–Z

  • Vat Yellow 4
  • Vinblastine sulfate
  • Vincristine sulfate
  • Vinyl chloride-vinyl acetate copolymers
  • Vinylidene chloride-vinyl chloride copolymers
  • Vinylidene fluoride
  • N-Vinyl-2-pyrrolidone
  • Vinyl toluene
  • Vitamin K substances
  • Wollastonite
  • Xylenes
  • 2,4-Xylidine
  • 2,5-Xylidine
  • Yellow AB
  • Yellow OB
  • Zectran
  • Zeolites other than erionite (clinoptilolite, phillipsite, mordenite, non-fibrous Japanese zeolite, synthetic zeolites)
  • Zineb
  • Ziram

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