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Face masks during the COVID-19 pandemic

Health control procedure against COVID-19

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Through COVID-19 pandemic, Virus and Airborne transmission

In community and healthcare settings, the use of face masks was intended as source control to limit transmission of the virus and for personal protection to prevent infection. When properly worn, face masks can limit the respiratory droplets and aerosols that are spread by infected individuals, helping protect healthy individuals from infection.

Scientific studies concluded that the use of face masks was effective in protecting the individual using them against COVID-19. Various case-control and population-based studies also showed that the increased use of masks in a community reduced the spread of SARS-CoV-2, although there was a paucity of evidence from randomized controlled trials (RCTs). Masks varied in their effectiveness. Fitted N95s outperform surgical masks, while cloth masks provided marginal protection. During the public health emergency, governments widely recommended (and, in some jurisdictions, mandated) the wearing of masks. Prominent national and intergovernmental health agencies and their leaders recommended the use of masks to reduce transmission, including the WHO, American, European, and Chinese Centers for Disease Control and Prevention.

Types of masks

Many federal governmental agencies recommended using face masks to avoid COVID-19 transmission. Masks with exhalation valves were not recommended because they expelled the wearer's breath outwards, and an infected wearer might transmit the virus through the valve.

Various types of masks were in general use, each providing different levels of protection against COVID-19 transmission, ease of use, and comfort:

  • Cloth face masks
  • Surgical masks (medical masks)
  • Certified face-covering masks (filtering respirators) such as N95,N99, and FFP masks –– which required suitable fitting in hospital settings.
  • Other respirators, including elastomeric respirators, some of which may also be considered filtering masks

Other types of personal protective equipment (PPE), such as face shields and medical goggles, were used in conjunction with face masks but were not recommended as a replacement.

In 2020, shortages of facial masks led to the use of masks that were not certified and performed worse in particle filtration efficiency (PFE) tests.

Cloth masks

A cloth face mask is worn over the mouth and nose and made of common textiles such as cotton. These masks vary widely in effectiveness, depending on factors such as material, fit and seal, and number of layers. They are usually less effective at filtering than surgical masks and offer less protection. Unlike disposable masks, there are no required standards for cloth masks.

A study from 2020, which simulated the treatment of an artificially infected patient, found that a cloth mask was better than nothing, but not as good as a soft electret-filter surgical mask for protecting healthcare workers. Research on commonly available fabrics used in cloth masks found that cloth masks can provide significant protection against the transmission of particles in the aerosol size range, with enhanced performance across the nano-scale and micro-scale when masks use both mechanical and electrostatic-based filtration, but that leakage due to improper fit can degrade performance. A review of available research published in January 2021 concluded that cloth masks were considered adequate to protect healthcare practitioners in a clinical setting.

A study in 2013 had volunteers wear masks they made themselves from cotton T-shirts, following the pattern of a standard tie-behind-the-head surgical mask, and found the number of microscopic particles that leaked to the inside of the homemade masks was twice that of commercial masks. Wearing homemade masks also resulted in the leakage of a median of three times as many microorganisms as commercial masks. A 2020 study found that masks made of at least two layers of T-shirt fabric could be as protective against virus droplets as medical masks, and as breathable.

A 2020 peer-reviewed summary of published literature on the filtration properties of cloth and cloth masks recommended two to four layers of plain-weave cotton or flannel of at least 100 threads per inch. However, while increasing the number of layers (3-4) improves the filtration of the material, it makes breathing through the mask more difficult.

As of May 2020, there was no research on decontaminating and reusing cloth masks. The United States Centers for Disease Control and Prevention (CDC) recommended removing a mask by handling only the ear loops or ties, placing it directly in a washing machine, and immediately washing hands in soap and water for at least twenty seconds. Cold water is considered as effective as warm water for decontamination. The CDC also recommended washing hands before putting on the mask and again immediately after touching it.

There was no information on reusing an inter-layer filter. Disposing of filters after a single use was desirable. A narrative review of the literature on the filtration properties of cloth and other household materials did not find support for using a filter. A layer of cloth, if tolerated, was suggested instead, or a PM2.5 filter, as a third layer.

The United States Environmental Protection Agency (EPA) study published on 5 April 2021 showed extremely varied performance across cotton masks. The results of the EPA study found that "a three-layer knitted cotton mask blocked an average of 26.5 percent of particles in the chamber, while a washed, two-layer woven nylon mask with a filter insert and metal nose bridge blocked 79 percent of particles on average." Ultimately, the researchers found that fabric and fit are the two most vital factors when recommending masks to the public, and further research was being conducted on variables affecting mask fit such as facial hair and face shape.

Surgical masks

A surgical mask is a loose-fitting, disposable mask that creates a physical barrier separating the mouth and nose of the wearer from potential contaminants in the immediate environment. If worn properly, a surgical mask is meant to help block large-particle droplets, splashes, sprays, or splatter that may contain viruses and bacteria, keeping them from reaching the wearer's mouth and nose. Surgical masks may also help reduce others' exposure to the wearer's saliva and respiratory secretions.

Certified medical masks are made of non-woven material and are usually multi-layered. Filters may be made of microfibers with an electrostatic charge (electrets). An electret filter increases the chances that smaller particles will veer and hit a fiber, rather than going straight through (electrostatic capture). While there is some development work on making electret filtering materials that can be washed and reused, current commercially produced electret filters are ruined by many forms of disinfection, including washing with soap and water or alcohol, which destroys the electric charge. During the COVID-19 pandemic, public health authorities issued guidelines on how to save, disinfect and reuse electret-filter masks without damaging the filtration efficiency. Standard disposable surgical masks are not designed to be washed. Surgical masks may be labeled as surgical, isolation, dental, or medical procedure masks. The material that surgical masks are made from is worse at filtering very small particles (in the range of a tenth of a micrometer to a micrometer across) than that of filtering respirators (for example N95, FFP2), and the fit is worse. Surgical masks are made of a non-woven fabric created using a melt blowing process. Randomized controlled studies of respiratory infections like influenza find little difference in protection between surgical masks and filtering respirators. However, the filtering performance of correctly worn N95-type or FFP2-type filtering respirators have been shown to be superior to surgical or cloth masks. For preventing the transmission of influenza, work by the UK Health and Safety Executive found that live viruses penetrated all surgical masks tested, but properly fitted respirators reduced the viral dose by a factor of at least one hundred.

Surgical masks made to different standards in different regions of the world vary in the ranges of particles they filter. For example, the People's Republic of China regulates two types of such masks: single-use medical masks (Chinese standard YY/T 0969) and surgical masks (YY 0469). The latter masks are required to filter bacteria-sized particles (BFE ≥ 95%) and some virus-sized particles (PFE ≥ 30%), while the former masks are required to only filter bacteria-sized particles.

Modifications

The effectiveness of surgical masks in limiting particle transmission is a function of material and fit. Since the start of the COVID-19 pandemic, scientists have evaluated various modifications to ear loop surgical masks aimed at improving mask efficacy by reducing or eliminating gaps between the mask and face. The CDC evaluated and recommended two such modifications to ear loop masks to minimize the transmission of SARS-CoV-2. Under regular use, the CDC found that a surgical mask worn by a coughing individual blocked 41.3% of simulated cough aerosols (0.1–7.0μm particle size) from reaching a second individual six feet away. However, by applying a knot-and-tuck technique, 62.9% of particles were blocked. When the surgical mask was covered with a larger cloth mask, 82% of the particles were blocked. When both the source and recipient wore masks, 84% of the particles were blocked. The number increased to more than 95% when both parties either wore two masks (surgical mask with larger cloth mask) or used the knot-and-tuck technique.

Another modification was aimed at improving the comfort of the wearers. Early in the pandemic, healthcare workers were required to wear surgical masks for 12 or more hours per day. This caused the ear loops of the masks to chafe the back of their ears. Ear savers, plastic straps, and hooks that go around wearers' heads were invented to move the ear loops away from the wearer's ears. They could be made on demand by using a 3D printing process.

An improved version of the surgical mask approaches the efficacy of N95 respirators.

Filtering respirators

An N95 mask is a particulate-filtering respirator that meets the N95 air filtration rating of the United States National Institute for Occupational Safety and Health, meaning it filters at least 95% of 0.3μm airborne particles. While not resistant to oil like the P95, it is the most common particulate-filtering facepiece respirator.

The N95 mask is an example of a mechanical filter respirator, which provides protection against particulates, but not gases or vapors. Like the middle layer of surgical masks, the N95 mask is made of four layers of melt-blown, non-woven polypropylene fabric. The corresponding face mask used in the European Union is the FFP2 respirator.

Hard electret-filter masks like N95 and FFP masks must fit the face to provide full protection. Untrained users often get a reasonable fit, but fewer than one in four gets a perfect fit. Fit testing is thus standard, though debated. A line of petroleum jelly on the edge of the mask has been shown to reduce edge leakage in lab tests using mannequins that simulate breathing.

Some N95-series respirators, especially those intended for industrial use, have an exhalation valve to improve comfort, making exhalation easier and reducing leakage on exhalation and steaming up of glasses. However, those respirators are not reliable for the control of infected people (source control) in respiratory diseases such as COVID-19 because infected users (asymptomatic or not) would transmit the virus to others through the valve.

During the COVID-19 pandemic, there were shortages of filtering facepiece respirators, and they had to be used for extended periods and/or disinfected and reused. At the time, public health authorities issued guidelines on how to save, disinfect and reuse masks, as some disinfection methods damaged their filtration efficiency. Some hospitals stockpiled used masks as a precaution, and some had to sanitize and reuse masks.

Face shields and eye protection

The US Centers for Disease Control and Prevention (CDC) does not recommend the use of face shields as a substitute for masks to help slow the spread of COVID-19. In a study by Lindsley et al. (7 January 2021) funded by the National Institute for Occupational Safety and Health, face shields were found to block very few cough aerosols in contrast to face coverings such as cloth masks, procedure masks, and N95 respirators, indicating that face shields are not effective as source control devices for small respiratory aerosols and that face coverings are more effective than face shields as source control devices to reduce the community transmission of SARS-CoV-2.

In a scoping review, Godoy et al. (5 May 2020) said face shields are useful for barrier protection against splash and splatter contamination but should not be used as primary protection against respiratory disease transmission due to the lack of a peripheral seal. Instead, they should be used as an adjunct to other facial protection. The authors remarked that face shields have been used like this alongside medical-grade masks during the COVID-19 pandemic. They cited a cough simulation study by Lindsley et al. (2014) in which face shields were shown to reduce the risk of inhalation exposure by up to 95% immediately following aerosol production, but the protection was decreased with smaller aerosol particles and leakage of airborne particles around the sides of the shield.

There is only weak evidence that the use of eye protection, including face shields, is associated with lower rates of infection.

Elastomeric respirators

An elastomeric respirator is reusable personal protective equipment consisting of a tight-fitting half-facepiece or full-facepiece respirator with exchangeable filters such as cartridge filters. They provide an alternative respiratory protection option to filtering facepiece respirators such as N95 masks. Some healthcare workers have used them during supply shortages caused by the COVID-19 pandemic, as they can be reused over an extended period in healthcare settings. However, most elastomeric respirators have an unfiltered exhalation vent, which would allow the virus to spread from the wearer.

During the COVID-19 response, when supplies were limited, the US CDC said that contingency and crisis strategies should be followed: each elastomeric respirator is issued for the exclusive use of an individual healthcare provider but must be cleaned and disinfected as often as necessary to remain unspoiled and sanitary. If there is no other option than to share a respirator between healthcare providers, the respirator must be cleaned and disinfected before it is worn by a different individual. Filters (except for unprotected disc types) may be used for an extended period, but the filter housing of cartridge types must be disinfected after each patient interaction.

Powered air-purifying respirators

A powered air-purifying respirator (PAPR) is a type of personal protective equipment in which a device with a filter and fan creates a highly filtered airflow towards the headpiece and a positive outflow of air from the headpiece.

There is an increased risk for healthcare workers to become exposed to SARS-CoV-2 when they conduct aerosol-generating procedures on COVID-19 patients, which is why it is argued that such situations may require enhanced personal protective equipment (i.e., higher than N95) such as PAPRs for healthcare workers.

In a systematic review, Licina, Silvers, and Stuart (8 August 2020) said field studies indicate that there were equivalent rates of infection among healthcare workers who performed airway procedures on critically ill COVID-19 patients while the healthcare workers were using PAPRs or other appropriate respiratory equipment (such as N95 or FFP2). They remarked, though, that there is a need to further collect field data about optimal respiratory protection during highly virulent pandemics.

Face masks with exhalation valves

Some masks include an exhalation valve to expel the breath outwards, but that airflow is not filtered. Certification (as N95 or FFP2) is about the mask itself and does not warrant any safety about the air that is exhaled. Putting tape over the exhalation valve can make a mask or respirator as effective as one without a valve.

Scientists have visualized droplet dispersal for masks with exhalation valves and face shields and concluded that they can be ineffective against COVID-19 spread (e.g., after a cough) and recommended alternatives. A later study showed that some (but not all) respirators with exhalation valves can perform as well as a surgical mask. However, a respirator without an exhalation valve should still be preferred.

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