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History of science and technology in Japan

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Through Chemical reaction, Molecule and Electron

Science

In the natural sciences, the number of Japanese winners of the Nobel Prize has been second only to the United States in the 21st century, for contributions made in the 20th century. On the list of countries by research and development spending, Japan is third on the list, behind the United States and China.

Chemistry

Frontier Molecular Orbital Theory

In 1952, Kenichi Fukui published a paper in the Journal of Chemical Physics titled "A molecular theory of reactivity in aromatic hydrocarbons." He later received the 1981 Nobel Prize in Chemistry for his investigations into the mechanisms of chemical reactions, with his prize-winning work focused on the role of frontier orbitals in chemical reactions, specifically that molecules share loosely bonded electrons which occupy the frontier orbitals, that is the Highest Occupied Molecular Orbital (HOMO) and the Lowest Unoccupied Molecular Orbital (LUMO).

Chirally catalyzed hydrogenation

Ryōji Noyori was awarded the 2001 Nobel Prize in Chemistry for his "work on chirally catalyzed hydrogenation reactions" in 1968.

Proteins and enzymes

In the 1960s and 1970s, green fluorescent proteins (GFP), along with the separate luminescent protein aequorin (an enzyme that catalyzes the breakdown of luciferin, releasing light), was first purified from Aequorea victoria and its properties studied by Osamu Shimomura. He was awarded the 2008 Nobel Prize in Chemistry "for the discovery and development of the green fluorescent protein, GFP".

Koichi Tanaka was awarded the 2003 Nobel Prize in Chemistry for the development of soft laser desorption, "methods for identification and structure analyses of biological macromolecules" and for "soft desorption ionisation methods for mass spectrometric analyses of biological macromolecules". In 1987, he demonstrated that laser pulses could blast apart large protein molecules so that ions in gaseous form are produced.

Conductive polymers

Hideki Shirakawa was awarded the 2000 Nobel Prize in Chemistry "for the discovery and development of conductive polymers".

Mathematics

In the 1930s, while studying switching circuits, NEC engineer Akira Nakashima independently discovered Boolean algebra, which he was unaware of until 1938. In a series of papers published from 1934 to 1936, he formulated a two-valued Boolean algebra as a way to analyze and design circuits by algebraic means in terms of logic gates.

Medicine

In a landmark series of experiments beginning in 1976, Susumu Tonegawa showed that genetic material can rearrange itself to form the vast array of available antibodies. He later received the 1987 Nobel Prize in Physiology or Medicine "for his discovery of the genetic principle for generation of antibody diversity."

Physics

Particle physics

Hideki Yukawa predicted the existence of mesons in 1934, for which he later received the 1949 Nobel Prize in Physics. Yoichiro Nambu was awarded the 2008 Nobel Prize in Physics for his 1960 discovery of the mechanism of spontaneous broken symmetry in subatomic physics, related at first to the strong interaction's chiral symmetry (chiral symmetry breaking) and later to the electroweak interaction and Higgs mechanism.

The bottom quark is a product in almost all top quark decays, and is a frequent decay product for the Higgs boson. The bottom quark was theorized in 1973 by physicists Makoto Kobayashi and Toshihide Maskawa to explain CP violation. Toshihide Maskawa and Makoto Kobayashi's 1973 article, "CP Violation in the Renormalizable Theory of Weak Interaction", is the fourth most cited high energy physics paper of all time as of 2010. They discovered the origin of the explicit breaking of CP symmetry in the weak interactions. The Cabibbo–Kobayashi–Maskawa matrix, which defines the mixing parameters between quarks, was the result of this work. Kobayashi and Maskawa were awarded the 2008 Nobel Prize in Physics "for the discovery of the origin of the broken symmetry which predicts the existence of at least three families of quarks in nature."

Quantum physics

Leo Esaki was awarded the 1 Nobel Prize in Physics for the discovery of electron tunneling (quantum tunnelling) in the 1950s. The tunnel diode (Esaki diode) was invented in August 1957 by Leo Esaki, Yuriko Kurose and Takashi Suzuki when they were working at Tokyo Tsushin Kogyo, now Sony.

Shin'ichirō Tomonaga was awarded the 1965 Nobel Prize in Physics for his "fundamental work in quantum electrodynamics, with deep-ploughing consequences for the physics of elementary particles".

Astrophysics

Masatoshi Koshiba was awarded the 2002 Nobel Prize in Physics "for pioneering contributions to astrophysics, in particular for the detection of cosmic neutrinos" in the 1980s. He conducted pioneering work on solar neutrino detection, and Koshiba's work also resulted in the first real-time observation of neutrinos from the SN 1987A supernova. These efforts marked the beginning of neutrino astronomy.

Psychology

The Rashomon effect is where the same event is given contradictory interpretations by different individuals involved. The concept originates from Akira Kurosawa's 1950 film Rashomon, where a murder is described in four mutually contradictory ways by its four witnesses.

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